SCHEMBL8070167

SCHEMBL8070167

NC(CO)C(=O)NCC(=O)O

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.48
MAPT P10636 3/20 0.48
LMNA P02545 1/20 0.48
PTGS2 P35354 1/20 0.48
TDP1 Q9NUW8 1/20 0.48
PTGS1 P23219 1/20 0.42
GSTK1 Q9Y2Q3 1/20 0.42
ECE1 P42892 2/20 0.42
MME P08473 5/20 0.41
ACE P12821 3/20 0.41
CPA1 P15085 1/20 0.41
ACE2 Q9BYF1 1/20 0.41
GLO1 Q04760 1/20 0.37
FUCA1 P04066 1/20 0.36
HPGD P15428 1/20 0.36
MAPK1 P28482 1/20 0.36
HSD17B10 Q99714 1/20 0.36
MEN1 O00255 1/20 0.36
BLM P54132 1/20 0.36
NPEPPS P55786 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8070171 1.00 ALDH1A1 (0.48) ALDH1A1MAPTLMNAPTGS2TDP1
SCHEMBL9067361 1.00 ALDH1A1 (0.48) ALDH1A1MAPTLMNAPTGS2TDP1
SCHEMBL29385198 0.92 ALDH1A1 (0.42) ALDH1A1MAPTLMNAPTGS2TDP1
SCHEMBL29385408 0.92 ALDH1A1 (0.42) ALDH1A1MAPTLMNAPTGS2TDP1
SCHEMBL29386171 0.92 ALDH1A1 (0.42) ALDH1A1MAPTLMNAPTGS2TDP1
SCHEMBL5173973 0.92 ALDH1A1 (0.42) ALDH1A1MAPTLMNAPTGS2TDP1
SCHEMBL29385929 0.92 ALDH1A1 (0.42) ALDH1A1MAPTLMNAPTGS2TDP1
SCHEMBL10791516 0.92 ALDH1A1 (0.42) ALDH1A1MAPTLMNAPTGS2TDP1
SCHEMBL7746290 0.92 ALDH1A1 (0.42) ALDH1A1MAPTLMNAPTGS2TDP1
SCHEMBL5173963 0.92 ALDH1A1 (0.42) ALDH1A1MAPTLMNAPTGS2TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260116972-A1 CROSS-SPECIES-SPECIFIC PSCAXCD3, CD19XCD3, C-METXCD3, ENDOSIALINXCD3, EPCAMXCD3, IGF-1RXCD3 OR FAPALPHAXCD3 BISPECIFIC SINGLE CHAIN ANTIBODY AMGEN RES MUNICH GMBH (DE) 2026-04-30 US disclosed
US-20250163179-A1 CROSS-SPECIES-SPECIFIC PSMAxCD3 BISPECIFIC SINGLE CHAIN ANTIBODY AMGEN RESEARCH (MUNICH) GMBH (DE) 2025-05-22 US disclosed
US-12281172-B2 Cross-species-specific PSMAxCD3 bispecific single chain antibody AMGEN RESEARCH (MUNICH) GMBH (DE) 2025-04-22 US disclosed
US-11987633-B2 Cross-species-specific single domain bispecific single chain antibody AMGEN RESEARCH (MUNICH) GMBH (DE) 2024-05-21 US disclosed
US-20230357444-A1 CROSS-SPECIES-SPECIFIC BINDING DOMAIN AMGEN RES MUNICH GMBH (DE) 2023-11-09 US disclosed
EP-4180458-A1 CROSS-SPECIES-SPECIFIC PSMA X CD3 BISPECIFIC SINGLE CHAIN ANTIBODY Amgen Research (Munich) GmbH (DE) 2023-05-17 EP disclosed
US-20230037742-A1 CROSS-SPECIES-SPECIFIC PSMAxCD3 BISPECIFIC SINGLE CHAIN ANTIBODY AMGEN RESEARCH (MUNICH) GMBH (DE) 2023-02-09 US disclosed
EP-2155783-B2 CROSS-SPECIES-SPECIFIC CD3-EPSILON BINDING DOMAIN AMGEN RES MUNICH GMBH (DE) 2022-10-19 EP disclosed
US-11472886-B2 Cross-species-specific PSMAxCD3 bispecific single chain antibody AMGEN RESEARCH (MUNICH) GMBH (DE) 2022-10-18 US disclosed
EP-4059964-A1 CROSS-SPECIES-SPECIFIC BINDING DOMAIN Amgen Research (Munich) GmbH (DE) 2022-09-21 EP disclosed
JP-2022137063-A PEGYLATED PORCINE INTERFERON AND METHOD OF USE THEREOF エランコ・ユーエス・インコーポレイテッド 2022-09-21 JP disclosed
US-20220041736-A1 CROSS-SPECIES-SPECIFIC SINGLE DOMAIN BISPECIFIC SINGLE CHAIN ANTIBODY AMGEN RESEARCH (MUNICH) GMBH (DE) 2022-02-10 US disclosed
JP-2000016949-A THERAPEUTIC OR PROPHYLACTIC AGENT OF STOMATITIS, MUCOUS MEMBRANE DAMAGE OF DIGESTIVE TRACT OR CUTANEOUS ULCER NIPPON KAYAKU CO LTD 2000-01-18 JP disclosed
US-5736523-A ADMINISTERING TO THE MAMMAL SUFFERING FROM CANCER BIOCHEM PHARMA INC. (CA) 1998-04-07 US disclosed
US-5606037-A Processes antineoplastic heteronaphthoquinones BIOCHEM PHARMA INC. (CA) 1997-02-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260116972-A1 CROSS-SPECIES-SPECIFIC PSCAXCD3, CD19XCD3, C-METXCD3, ENDOSIALINXCD3, EPCAMXCD3, IGF-1RXCD3 OR FAPALPHAXCD3 BISPECIFIC SINGLE CHAIN ANTIBODY MET, IGF1R, INHA ALDH1A1 1470/4885MAPT 3876/4885LMNA 2911/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.