Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP9 | P14780 | 3/20 | 0.58 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.50 |
| ▸ | PLAU | P00749 | 1/20 | 0.48 |
| ▸ | HPN | P05981 | 1/20 | 0.48 |
| ▸ | USP30 | Q70CQ3 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.46 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.46 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.46 |
| ▸ | ITGAV | P06756 | 1/20 | 0.46 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | PRMT1 | Q99873 | 2/20 | 0.45 |
| ▸ | PLK1 | P53350 | 3/20 | 0.45 |
| ▸ | PLK3 | Q9H4B4 | 3/20 | 0.45 |
| ▸ | F2 | P00734 | 1/20 | 0.45 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.45 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.45 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.45 |
| ▸ | MMP2 | P08253 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8193360 | 0.89 | MMP9 (0.62) | MMP9TRPV1PLAUHPNUSP30 | |
| SCHEMBL6424104 | 0.89 | MMP9 (0.62) | MMP9TRPV1PLAUHPNUSP30 | |
| SCHEMBL7590434 | 0.88 | MMP9 (0.75) | MMP9TRPV1KDM4EITGB3ITGA2B | |
| SCHEMBL7583683 | 0.84 | MMP9 (0.58) | MMP9TRPV1PLAUHPNUSP30 | |
| SCHEMBL7663396 | 0.75 | MMP9 (0.71) | MMP9USP30ITGB3ITGA2BITGB1 | |
| SCHEMBL7665147 | 0.75 | MMP9 (0.71) | MMP9USP30ITGB3ITGA2BITGB1 | |
| SCHEMBL7668862 | 0.75 | MMP9 (1.00) | MMP9ITGB3ITGA2BITGB1ITGAV | |
| SCHEMBL7675244 | 0.75 | MMP9 (1.00) | MMP9ITGB3ITGA2BITGB1ITGAV | |
| SCHEMBL9506968 | 0.75 | NPC1 (0.64) | TRPV1PLK1PLK3 | |
| SCHEMBL5093780 | 0.74 | MMP9 (1.00) | MMP9PLAUHPNITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6022893-A | PREVENTION AND TREATMENT OF DISEASES INDUCED BY OVEREXPRESSION OR EXCESS ACTIVATION OF GELATINASES | ONO PHARMACEUTICAL CO., LTD. (JP) | 2000-02-08 | — | — | US | claimed |