Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 8/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | TP53 | P04637 | 3/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4369137 | 0.83 | TSHR (0.57) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL11424258 | 0.82 | TSHR (0.50) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL184856 | 0.81 | TSHR (0.60) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL3251563 | 0.81 | TSHR (0.59) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL27669542 | 0.80 | TSHR (0.51) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL10306277 | 0.77 | TSHR (0.50) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL20359743 | 0.77 | TSHR (0.50) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL27821519 | 0.76 | — | — | |
| SCHEMBL27800525 | 0.76 | — | — | |
| SCHEMBL33585 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0106193-A2 | Liquid skin cleanser composition | UNION CARBIDE CORPORATION (US) | 1984-04-25 | — | — | EP | claimed |
| US-6063368-A | MIXTURE OF FOAMING AGENT, WATER SOLUBLE FILM FORMING QUATERNIZED POLYMER AND WATER | AVEDA CORPORATION (US) | 2000-05-16 | — | — | US | disclosed |
| US-4465802-A | WITH WATER SOLUBLE CATIONIC POLYMER AND CATIONIC SURFACTANT | UNION CARBIDE CORPORATION (US) | 1984-08-14 | — | — | US | disclosed |
| US-4362528-A | OXIDATION COLOR DYE,CATIONIC POLYMER TO IMPROVE FEEL,SHAMPOO WITH ANIONIC DETERGENT | SOCIETE ANONYME DITE: L'OREAL (FR) | 1982-12-07 | — | — | US | disclosed |
| US-4314807-A | CATIONIC POLYMER, ANIONIC SURFACTANT SHAMPOO | L'OREAL (FR) | 1982-02-09 | — | — | US | disclosed |
| US-3980769-A | ANIONIC AND AMPHOTERIC SURFACTANTS | L'OREAL (FR) | 1976-09-14 | — | — | US | disclosed |
| US-3958581-A | Cosmetic composition containing a cationic polymer and divalent metal salt for strengthening the hair | L'OREAL (FR) | 1976-05-25 | — | — | US | disclosed |