SCHEMBL184856

SCHEMBL184856

C=CC(=O)OCC(C)N(CC)CC

nearest known ligand 0.60

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TSHR P16473 8/20 0.60
HPGD P15428 1/20 0.44
ALDH1A1 P00352 5/20 0.39
TP53 P04637 3/20 0.39
HIF1A Q16665 3/20 0.39
CYP3A4 P08684 2/20 0.39
HSD17B10 Q99714 1/20 0.39
THRB P10828 3/20 0.38
MAPK1 P28482 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
HCAR2 Q8TDS4 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1683537 0.89 TSHR (0.49) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL21925316 0.88 TSHR (0.47) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL21925357 0.86 TSHR (0.56) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL15422805 0.84 TSHR (0.58) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL4369137 0.83 TSHR (0.57) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL9621717 0.83 TSHR (0.54) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL12860046 0.82 TSHR (0.56) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL8070296 0.81 TSHR (0.55) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL373261 0.81 TSHR (0.64) TSHRHPGDALDH1A1TP53HIF1A
Hydrochloric Acid SCHEMBL7722236 0.79 TSHR (0.62) TSHRHPGDALDH1A1TP53HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 115 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170320992-A1 POLY(ALKYLENE CARBONATE)-BASED AMPHIPHILIC BLOCK COPOLYMERS AND METHODS OF USE THEREOF PURDUE RESEARCH FOUNDATION (US) 2017-11-09 US claimed
WO-2016077614-A1 POLY(ALKYLENE CARBONATE)-BASED AMPHIPHILIC BLOCK COPOLYMERS AND METHODS OF USE THEREOF PURDUE RESEARCH FOUNDATION (US) 2016-05-19 WO claimed
US-12351738-B2 Binder compositions and uses thereof KNAUF INSULATION, INC. (US) 2025-07-08 US disclosed
EP-3169733-B1 IMPROVED BINDER COMPOSITIONS AND USES THEREOF KNAUF INSULATION SPRL (BE) 2024-10-16 EP disclosed
US-11879063-B2 Binder compositions and uses thereof KNAUF INSULATION, INC. 2024-01-23 US disclosed
US-11413846-B2 Article featuring a predetermined pattern of randomly distributed microspheres and methods of making the same 3M INNOVATIVE PROPERTIES COMPANY (US) 2022-08-16 US disclosed
US-20220098452-A1 BINDER COMPOSITIONS AND USES THEREOF KNAUF INSULATION, INC. 2022-03-31 US disclosed
US-20210340379-A1 Binder Compositions and Uses Thereof KNAUF INSULATION SPRL (BE) 2021-11-04 US disclosed
US-11112544-B2 Truncated beadfilm constructions and methods of making the same 3M INNOVATIVE PROPERTIES COMPANY (US) 2021-09-07 US disclosed
US-20210214557-A1 Binder Compositions and Uses Thereof KNAUF INSULATION, INC. 2021-07-15 US disclosed
US-20210087401-A1 Binder Compositions and Uses Thereof KNAUF INSULATION SPRL (BE) 2021-03-25 US disclosed
US-4157947-A Coating and ink compositions and method UNION CARBIDE CORPORATION (US) 1979-06-12 US disclosed
US-4025477-A RADIATION CURABLE INKS AND COATINGS UNION CARBIDE CORPORATION (US) 1977-05-24 US disclosed
US-4016059-A RADIATION UNION CARBIDE CORPORATION (US) 1977-04-05 US disclosed
US-4006024-A Photosensitive compositions comprising a polyester-polyether block polymer ASAHI KASEI KOGYO KABUSHIKI KAISHA (JA) 1977-02-01 US disclosed
US-RE29131-E CURED TO PROTECTIVE COATINGS UNION CARBIDE CORPORATION (US) 1977-02-01 US disclosed
US-3979270-A Method for curing acrylated epoxidized soybean oil amine compositions UNION CARBIDE CORPORATION (US) 1976-09-07 US disclosed
US-3960572-A Photosensitive compositions comprising a polyester-polyether block polymer ASAHI KASEI KOGYO KABUSHIKI KAISHA (JA) 1976-06-01 US disclosed
US-3931071-A COMPOSITIONS OF ACRYLATED EPOXIDIZED SOYBEAN OIL AMINE COMPOUNDS USEFUL AS INKS AND COATINGS UNION CARBIDE CORPORATION (US) 1976-01-06 US disclosed
US-3931075-A INKS, COATINGS UNION CARBIDE CORPORATION (US) 1976-01-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170320992-A1 POLY(ALKYLENE CARBONATE)-BASED AMPHIPHILIC BLOCK COPOLYMERS AND METHODS OF USE THEREOF PARG, PICALM, PHOSPHO1 TSHR 4590/4885HPGD 4027/4885ALDH1A1 4855/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.