Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | PNMT | P11086 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11589997 | 0.70 | ALDH1A1 (0.41) | ALDH1A1MEN1LMNAMAPTHTT | |
| SCHEMBL22624887 | 0.70 | — | — | |
| SCHEMBL27887717 | 0.68 | ALDH1A1 (0.32) | ALDH1A1MEN1LMNAMAPTHTT | |
| SCHEMBL939745 | 0.67 | — | — | |
| SCHEMBL11455703 | 0.67 | — | — | |
| SCHEMBL12050713 | 0.67 | — | — | |
| SCHEMBL9370007 | 0.64 | ALDH1A1 (0.33) | ALDH1A1MEN1LMNAMAPTHTT | |
| SCHEMBL7687591 | 0.63 | ALDH1A1 (0.34) | ALDH1A1MEN1LMNAMAPTHTT | |
| SCHEMBL8586032 | 0.63 | ALDH1A1 (0.44) | ALDH1A1MEN1LMNAMAPTHTT | |
| SCHEMBL22950993 | 0.63 | ALDH1A1 (0.39) | ALDH1A1LMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0821676-B1 | 3-PHENYL-1,4-DIALKYL-1,2,4-TRIAZOLIUM SALTS AND THEIR USE AS ANTIDEPRESSANTS | AVENTIS PHARMA INC (US) | 2000-07-05 | — | — | EP | disclosed |
| US-5856350-A | PSYCHOLOGICAL DISORDERS | HOECHST MARION ROUSSEL, INC. (US) | 1999-01-05 | — | — | US | disclosed |
| EP-0821676-A1 | 3-PHENYL-1,4-DIALKYL-1,2,4-TRIAZOLIUM SALTS AND THEIR USE AS ANTIDEPRESSANTS | HOECHST MARION ROUSSEL, INC. (US) | 1998-02-04 | — | — | EP | disclosed |
| WO-1996033177-A1 | 3-PHENYL-1,4-DIALKYL-1,2,4-TRIAZOLIUM SALTS AND THEIR USE AS ANTIDEPRESSANTS | HOECHST MARION ROUSSEL, INC. (US) | 1996-10-24 | — | — | WO | disclosed |
| US-5260450-A | Anticonvulsants | MERRELL DOW PHARMACEUTICALS INC. (US) | 1993-11-09 | — | — | US | disclosed |
| US-5158968-A | 3-aryl-5-alkylthio-4H-1,2,4-traizoles for treatment of hyperreflexia due to spinal trauma | MERRELL DOW PHARMACEUTICALS INC. (US) | 1992-10-27 | — | — | US | disclosed |
| US-5143933-A | Anticonvulsants | MERRELL DOW PHARMACEUTICALS INC. (US) | 1992-09-01 | — | — | US | disclosed |
| EP-0495226-A2 | 3-Aryl-5-alkylthio-4H-1,2,4-triazoles for treatment of hyperreflexia due to spinal trauma | MERRELL DOW PHARMACEUTICALS INC. (US) | 1992-07-22 | — | — | EP | disclosed |