Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | PNMT | P11086 | 1/20 | 0.32 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2010779 | 0.76 | ALDH1A1 (0.39) | ALDH1A1KDM4ETXNRD1SMN1; SMN2 | |
| SCHEMBL4686081 | 0.76 | ALDH1A1 (0.34) | ALDH1A1TXNRD1SMN1; SMN2 | |
| SCHEMBL27572775 | 0.75 | TXNRD1 (0.33) | TXNRD1 | |
| SCHEMBL4686083 | 0.75 | TBXAS1 (0.36) | ALDH1A1KDM4ETXNRD1SMN1; SMN2 | |
| SCHEMBL8141707 | 0.74 | KDM4E (0.58) | KDM4EMEN1MAPTHTTKMT2A | |
| SCHEMBL9370010 | 0.74 | TXNRD1 (0.38) | MEN1KMT2ATXNRD1 | |
| SCHEMBL4682203 | 0.73 | TAAR1 (0.33) | ALDH1A1TXNRD1SMN1; SMN2 | |
| SCHEMBL4682206 | 0.72 | CA2 (0.36) | ALDH1A1POLBTXNRD1SMN1; SMN2 | |
| SCHEMBL1727030 | 0.71 | — | — | |
| SCHEMBL502541 | 0.71 | TXNRD1 (0.44) | ALDH1A1KDM4ETXNRD1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12366579-B2 | Sulfur-heterocycle exchange chemistry and uses thereof | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) | 2025-07-22 | — | — | US | disclosed |
| US-20220214355-A1 | SULFUR-HETEROCYCLE EXCHANGE CHEMISTRY AND USES THEREOF | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) | 2022-07-07 | — | — | US | disclosed |
| US-4163839-A | INHIBITION OF DEAMINATING ENZYMES WHICH INACTIVATE FORMYCIN AND ADENINE ARABINOSIDE | Zaidan Hojin Biselbutsu Kagaku Kenkyu Kai (JP) | 1979-08-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220214355-A1 | SULFUR-HETEROCYCLE EXCHANGE CHEMISTRY AND USES THEREOF | TST, TPST2, SRMS | ALDH1A1 3058/4885KDM4E 1916/4885MEN1 3852/4885 |
| US-12366579-B2 | Sulfur-heterocycle exchange chemistry and uses thereof | TST, TPST2, SRMS | ALDH1A1 3058/4885KDM4E 1916/4885MEN1 3852/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.