Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.43 |
| ▸ | IDO1 | P14902 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | PRCP | P42785 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL145977 | 0.82 | IDO1 (0.57) | SIGMAR1IDO1HTTTSHRLMNA | |
| SCHEMBL29357487 | 0.82 | IDO1 (0.57) | SIGMAR1IDO1HTTTSHRLMNA | |
| SCHEMBL6784204 | 0.79 | IDO1 (0.53) | SIGMAR1IDO1 | |
| SCHEMBL16817775 | 0.75 | MAPT (0.41) | SIGMAR1MEN1KMT2ATSHRLMNA | |
| SCHEMBL10785005 | 0.75 | SIGMAR1 (0.60) | SIGMAR1IDO1PRCP | |
| SCHEMBL4661810 | 0.74 | SIGMAR1 (0.63) | SIGMAR1IDO1EPHX1PRCP | |
| SCHEMBL21924071 | 0.74 | SIGMAR1 (0.63) | SIGMAR1IDO1EPHX1PRCP | |
| SCHEMBL30285859 | 0.74 | SIGMAR1 (0.63) | SIGMAR1IDO1EPHX1PRCP | |
| SCHEMBL6542145 | 0.74 | SIGMAR1 (0.63) | SIGMAR1IDO1EPHX1PRCP | |
| SCHEMBL6275122 | 0.74 | MAPT (0.40) | MEN1KMT2ATSHRPRCPLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6025177-A | ENANTIOSELECTIVE SYNTHESIS OF CHIRAL ALPHA-HYDROXYCARBOXYLATE BY REACTING A PROCHIRAL ALPHA-KETOCARBOXYLIC ACID WITH A SINGLE ENANTIOMER OF AN N-SUBSTITUTED VICINAL AMINOALCOHOL OF SPECIFIC CYCLOHYDROCARBONS TO FORM ALPHA-HYDROXYCARBOXYLATE | SEPRACOR INC. (US) | 2000-02-15 | — | — | US | disclosed |