Pyrogallol

Pyrogallol

SCHEMBL8070517

C=CC(=O)O.Oc1cccc(O)c1O

nearest known ligand 0.57

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 4/20 0.57
CA2 P00918 4/20 0.57
LMNA P02545 3/20 0.57
ALDH1A1 P00352 3/20 0.57
HPGD P15428 3/20 0.57
CA6 P23280 2/20 0.57
ALOX15 P16050 2/20 0.57
HSD17B10 Q99714 2/20 0.57
ADAMTS4 O75173 1/20 0.57
EGFR P00533 1/20 0.57
FYN P06241 1/20 0.57
MMP2 P08253 1/20 0.57
MMP9 P14780 1/20 0.57
MMP8 P22894 1/20 0.57
CDK2 P24941 1/20 0.57
MMP12 P39900 1/20 0.57
RECQL P46063 1/20 0.57
TDP1 Q9NUW8 1/20 0.57
ADAMTS5 Q9UNA0 1/20 0.57
ERN1 O75460 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Pyrogallol SCHEMBL11135801 0.92 CA1 (0.48) CA1CA2LMNAALDH1A1HPGD
2,3-Dihydroxybenzoic Acid SCHEMBL30341693 0.86 SELL (0.55) CA1CA2LMNAALDH1A1HPGD
2,3-Dihydroxybenzoic Acid SCHEMBL28987271 0.86 SELL (0.55) CA1CA2LMNAALDH1A1HPGD
Catechol SCHEMBL30859528 0.85 KDM4E (0.53) CA1CA2LMNAALDH1A1HPGD
Catechol SCHEMBL19181220 0.85 KDM4E (0.53) CA1CA2LMNAALDH1A1HPGD
Pyrogallol SCHEMBL17183664 0.84 ALDH1A1 (0.55) CA1CA2LMNAALDH1A1HPGD
Catechol SCHEMBL27718884 0.83 KDM4E (0.50) CA1CA2LMNAALDH1A1HPGD
Acrylic Acid SCHEMBL23161029 0.82 HNF4A (0.53) CA1CA2LMNAALDH1A1HPGD
Pyrogallol SCHEMBL30940426 0.82 ALDH1A1 (0.52) CA1CA2LMNAALDH1A1HPGD
Pyrogallol SCHEMBL30940450 0.82 ALDH1A1 (0.52) CA1CA2LMNAALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0756204-B1 Photopolymerizable composition and photosensitive lithographic printing plate employing it MITSUBISHI CHEM CORP (JP) 2000-09-20 EP disclosed
US-5837422-A ON A SUSTRATE CONTATINING ADDITION POLYMERIZABLE UNSATURATED BONDS WITH AND WITHOUT URETHANE BONDS; HIGH SENSITIVITY TO LIGNT IN VISIBLE REGION AND EXCELLENT DEVELOPABILITY MITSUBISHI CHEMICAL CORPORATION (JP) 1998-11-17 US disclosed
EP-0756204-A1 Photopolymerizable composition and photosensitive lithographic printing plate employing it MITSUBISHI CHEMICAL CORPORATION (JP) 1997-01-29 EP disclosed
US-4910119-A Blend of acrylated ester, unsaturated compound and photoinitiator HOECHST AKTIENGESELLSCHAFT (DE) 1990-03-20 US disclosed
US-4554346-A REACTION WITH UNSATURATED HYDROXY COMPOUND MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1985-11-19 US disclosed