SCHEMBL8070666

SCHEMBL8070666

O=C(C(=O)c1ccc(F)cc1F)c1ccc(F)cc1F

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CES2 O00748 8/20 1.00
CES1 P23141 8/20 1.00
L3MBTL1 Q9Y468 1/20 0.49
SNCA P37840 1/20 0.46
CYP11B1 P15538 1/20 0.45
CYP11B2 P19099 1/20 0.45
NPC1 O15118 1/20 0.45
RAB9A P51151 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7999846 0.89 CES2 (0.80) CES2CES1L3MBTL1SNCARAB9A
SCHEMBL7715988 0.89 CES2 (0.79) CES2CES1L3MBTL1SNCACYP11B1
SCHEMBL7777968 0.87 CES2 (0.76) CES2CES1L3MBTL1SNCACYP11B1
SCHEMBL13291390 0.85 CES2 (0.74) CES2CES1L3MBTL1SNCANPC1
SCHEMBL366061 0.83 CES2 (0.71) CES2CES1L3MBTL1SNCANPC1
SCHEMBL7612594 0.83 CES2 (0.71) CES2CES1L3MBTL1SNCANPC1
SCHEMBL5605898 0.83 CES2 (0.71) CES2CES1L3MBTL1SNCANPC1
SCHEMBL3184249 0.82 CES2 (0.68) CES2CES1L3MBTL1SNCACYP11B1
SCHEMBL12511048 0.81 CES2 (0.68) CES2CES1L3MBTL1SNCANPC1
SCHEMBL4962246 0.81 CES2 (0.68) CES2CES1L3MBTL1SNCANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0596395-B1 Process for the preparation of fluorinated benzil CLARIANT GMBH (DE) 2000-06-28 EP disclosed
US-5463135-A Fluorinated benzils and a process for their preparation HOECHST AKTIENGESELLSCHAFT (DE) 1995-10-31 US disclosed
EP-0596395-A1 Fluorinated benzils and process for their preparation HOECHST AKTIENGESELLSCHAFT (DE) 1994-05-11 EP disclosed