Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 2/20 | 0.51 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.51 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.51 |
| ▸ | BACE1 | P56817 | 4/20 | 0.47 |
| ▸ | CTSD | P07339 | 2/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.45 |
| ▸ | GSTK1 | Q9Y2Q3 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | ACE | P12821 | 2/20 | 0.43 |
| ▸ | MME | P08473 | 5/20 | 0.38 |
| ▸ | CPA1 | P15085 | 1/20 | 0.38 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.38 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.36 |
| ▸ | FNTA | P49354 | 1/20 | 0.36 |
| ▸ | FNTB | P49356 | 1/20 | 0.36 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8070743 | 0.90 | DPP4 (0.52) | DPP4DPP8DPP9BACE1CTSD | |
| SCHEMBL8070735 | 0.90 | DPP4 (0.52) | DPP4DPP8DPP9BACE1CTSD | |
| SCHEMBL29630514 | 0.90 | DPP4 (0.55) | DPP4DPP8DPP9BACE1CTSD | |
| SCHEMBL31721065 | 0.89 | BACE1 (0.46) | DPP4DPP8DPP9BACE1CTSD | |
| SCHEMBL29420040 | 0.88 | ALOX15 (0.50) | DPP4DPP8DPP9BACE1CTSD | |
| SCHEMBL3065655 | 0.88 | DPP4 (0.63) | DPP4DPP8DPP9BACE1CTSD | |
| SCHEMBL751144 | 0.88 | DPP4 (0.63) | DPP4DPP8DPP9BACE1CTSD | |
| SCHEMBL31571449 | 0.87 | BACE1 (0.58) | DPP4DPP8DPP9BACE1CTSD | |
| SCHEMBL29777801 | 0.87 | DPP4 (0.52) | DPP4DPP8DPP9BACE1CTSD | |
| SCHEMBL30193486 | 0.87 | DPP4 (0.52) | DPP4DPP8DPP9BACE1CTSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1015603-A2 | NEW PLANT GENES | RHONE-POULENC AGRICULTURE LTD. (GB) | 2000-07-05 | — | — | EP | disclosed |
| WO-1999014337-A2 | NEW PLANT GENES | RHONE-POULENC AGRICULTURE LIMITED (GB) | 1999-03-25 | — | — | WO | disclosed |