SCHEMBL751144

SCHEMBL751144

C[C@H](NC(=O)[C@@H](N)CCC(N)=O)C(=O)O

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 3/20 0.63
DPP8 Q6V1X1 3/20 0.63
DPP9 Q86TI2 3/20 0.63
ALOX15 P16050 1/20 0.57
BLM P54132 1/20 0.57
PMP22 Q01453 1/20 0.57
KMT2A Q03164 1/20 0.57
BACE1 P56817 3/20 0.46
CTSD P07339 2/20 0.46
ACE P12821 2/20 0.42
MME P08473 2/20 0.42
CPA1 P15085 1/20 0.42
ACE2 Q9BYF1 1/20 0.42
GRM8 O00222 1/20 0.39
GRM6 O15303 1/20 0.39
GRIN2D O15399 1/20 0.39
GRIN3B O60391 1/20 0.39
GSR P00390 1/20 0.39
CYP1A2 P05177 1/20 0.39
GRIK1 P39086 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3065655 1.00 DPP4 (0.63) DPP4DPP8DPP9ALOX15BLM
Hydrochloric Acid SCHEMBL23404089 0.98 DPP4 (0.61) DPP4DPP8DPP9ALOX15BLM
SCHEMBL29499873 0.97 DPP4 (0.59) DPP4DPP8DPP9ALOX15BLM
SCHEMBL29630514 0.92 DPP4 (0.55) DPP4DPP8DPP9ALOX15BLM
SCHEMBL30193486 0.89 DPP4 (0.52) DPP4DPP8DPP9ALOX15BLM
SCHEMBL31571449 0.89 BACE1 (0.58) DPP4DPP8DPP9ALOX15BLM
SCHEMBL29777801 0.89 DPP4 (0.52) DPP4DPP8DPP9ALOX15BLM
SCHEMBL8070748 0.88 DPP4 (0.51) DPP4DPP8DPP9ALOX15BLM
SCHEMBL31031607 0.88 BACE1 (0.54) DPP4DPP8DPP9ALOX15BLM
SCHEMBL29478400 0.88 BACE1 (0.54) DPP4DPP8DPP9ALOX15BLM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 250 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260124212-A1 MAYTANSINOID DERIVATIVES WITH SELF-IMMOLATIVE PEPTIDE LINKERS AND CONJUGATES THEREOF IMMUNOGEN INC (US) 2026-05-07 US claimed
EP-4676457-A1 PROTECTIVE AMINOACID AGENTS FOR USE IN PERITONEAL DIALYSIS Zytoprotec Flexible Kapitalgesellschaft (AT) 2026-01-14 EP claimed
US-12390471-B2 Maytansinoid derivatives with self-immolative peptide linkers and conjugates thereof IMMUNOGEN, INC. (US) 2025-08-19 US claimed
EP-4551267-A1 PERITONEAL DIALYSIS FLUID Zytoprotec Flexible Kapitalgesellschaft (AT) 2025-05-14 EP claimed
CN-118897023-B Method for directly measuring alpha and gamma-glutamyl peptide in skeletal muscle by using LC-MS and isotope dilution assay 中国农业科学院北京畜牧兽医研究所 2025-03-25 CN claimed
CN-119104584-A Diagnostic model and application thereof in diagnosis of aortic aneurysm 首都医科大学附属北京友谊医院 2024-12-10 CN claimed
CN-118897023-A Method for directly measuring alpha and gamma-glutamyl peptide in skeletal muscle by using LC-MS and isotope dilution assay 中国农业科学院北京畜牧兽医研究所 2024-11-05 CN claimed
WO-2024184220-A1 PROTECTIVE AMINOACID AGENTS FOR USE IN PERITONEAL DIALYSIS ZYTOPROTEC GMBH (AT) 2024-09-12 WO claimed
EP-4424307-A1 PROTECTIVE AGENT FOR USE IN PERITONEAL DIALYSIS Zytoprotec GmbH (AT) 2024-09-04 EP claimed
US-20240226312-A1 TREATMENT OF CANCER IN PATIENTS WITH SOLUBLE FR-ALPHA IMMUNOGEN, INC. (US) 2024-07-11 US claimed
WO-2016196743-A1 METHODS AND SYSTEMS FOR DETECTING MELANOMA THE UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2016-12-08 WO claimed
US-20140142051-A1 CARBOHYDRATE-BASED PERITONEAL DIALYSIS FLUID COMPRISING GLUTAMINE RESIDUE ZYTOPROTEC GMBH (AT) 2014-05-22 US claimed
EP-2640423-A1 LIPOYL COMPOUNDS AND THEIR USE FOR TREATING ISCHEMIC INJURY Ischemix LLC (US) 2013-09-25 EP claimed
EP-2129370-B1 Carbohydrate-based peritoneal dialysis fluid comprising glutamine residue ZYTOPROTEC GMBH (AT) 2012-11-21 EP claimed
WO-2012067947-A1 LIPOYL COMPOUNDS AND THEIR USE FOR TREATING ISCHEMIC INJURY ISCHEMIX LLC (US) 2012-05-24 WO claimed
US-20100099628-A1 CARBOHYDRATE-BASED PERITONEAL DIALYSIS FLUID COMPRISING GLUTAMINE RESIDUE ZYTO-PROTEC GMBH (AT) 2010-04-22 US claimed
EP-2129370-A1 CARBOHYDRATE-BASED PERITONEAL DIALYSIS FLUID COMPRISING GLUTAMINE RESIDUE Zytoprotec Gmbh (AT) 2009-12-09 EP claimed
WO-2008106702-A1 CARBOHYDRATE-BASED PERITONEAL DIALYSIS FLUID COMPRISING GLUTAMINE RESIDUE ZYTOPROTEC GMBH (AT) 2008-09-12 WO claimed
EP-0457314-A1 Nutrient compositions containing peptides CLINTEC NUTRITION COMPANY (US) 1991-11-21 EP claimed
US-4987123-A L-ALANINE AND L-GLUTAMINE OR SALTS OR PEPTIDES THEREOF AJINOMOTO CO., INC. (JP) 1991-01-22 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12390471-B2 Maytansinoid derivatives with self-immolative peptide linkers and conjugates thereof VIP, AREG, MIF DPP4 1262/4885DPP8 3390/4885DPP9 2149/4885
US-20240226312-A1 TREATMENT OF CANCER IN PATIENTS WITH SOLUBLE FR-ALPHA FOLR1, FOLR2, FRS2 DPP4 4488/4885DPP8 3928/4885DPP9 3873/4885
US-20260124212-A1 MAYTANSINOID DERIVATIVES WITH SELF-IMMOLATIVE PEPTIDE LINKERS AND CONJUGATES THEREOF VEGFA, VIP, AREG DPP4 2235/4885DPP8 3838/4885DPP9 3056/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.