Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALK | Q9UM73 | 6/20 | 0.40 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.40 |
| ▸ | CDK9 | P50750 | 1/20 | 0.40 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.39 |
| ▸ | SUV39H2 | Q9H5I1 | 7/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.38 |
| ▸ | WNT3A | P56704 | 1/20 | 0.37 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.37 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8075391 | 0.88 | CCNT1 (0.42) | ALKCCNT1CDK9GPR119PDE3B | |
| SCHEMBL8074046 | 0.85 | ATP1A1 (0.35) | PDE3BPDE3AALDH1A1LMNAMAPT | |
| SCHEMBL8069116 | 0.83 | NPC1 (0.44) | ALKCCNT1CDK9P2RX7SUV39H2 | |
| SCHEMBL8469710 | 0.79 | ATP4A (0.37) | ALDH1A1LMNAMAPT | |
| Ilaprazole SCHEMBL23988478 | 0.78 | ATP1A1 (0.36) | ABCB1ALDH1A1LMNAMAPT | |
| Ilaprazole SCHEMBL22734706 | 0.78 | ATP1A1 (0.36) | ABCB1ALDH1A1LMNAMAPT | |
| Ilaprazole SCHEMBL22734704 | 0.78 | ATP1A1 (0.36) | ABCB1ALDH1A1LMNAMAPT | |
| Ilaprazole SCHEMBL1179039 | 0.78 | ATP1A1 (0.36) | ABCB1ALDH1A1LMNAMAPT | |
| SCHEMBL14467743 | 0.78 | ATP4A (0.37) | — | |
| Ilaprazole SCHEMBL8470106 | 0.77 | ATP1A1 (0.36) | ABCB1ALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6051570-A | ANTIULCER AGENTS | DR. REDDY'S RESEARCH FOUNDATION (IN) | 2000-04-18 | — | — | US | claimed |
| US-6051570-A | ANTIULCER AGENTS | DR. REDDY'S RESEARCH FOUNDATION (IN) | 2000-04-18 | — | — | US | disclosed |
| EP-0983263-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES AS ANTIULCER AGENTS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | DR. REDDY'S RESEARCH FOUNDATION (IN) | 2000-03-08 | — | — | EP | disclosed |
| WO-1998054172-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES AS ANTIULCER AGENTS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | DR. REDDY'S RESEARCH FOUNDATION (IN) | 1998-12-03 | — | — | WO | disclosed |