Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 15/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 7/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.42 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.40 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.40 |
| ▸ | PGR | P06401 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.40 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.40 |
| ▸ | SLC47A1 | Q96FL8 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8075621 | 0.81 | CHRM3 (0.36) | CHRM3CHRM2KCNH2CHRM1CYP2D6 | |
| SCHEMBL9295790 | 0.68 | CHRM3 (0.59) | CHRM3CHRM2KCNH2CHRM1LMNA | |
| SCHEMBL2341114 | 0.68 | CHRM3 (0.46) | CHRM3CHRM2KCNH2CHRM1LMNA | |
| SCHEMBL2205198 | 0.67 | CHRM3 (0.51) | CHRM3CHRM2KCNH2CHRM1LMNA | |
| SCHEMBL8880729 | 0.67 | KMT2A (0.47) | CHRM3CHRM2KCNH2CHRM1LMNA | |
| Hydrochloric Acid SCHEMBL5521545 | 0.67 | CHRM3 (0.45) | CHRM3CHRM2KCNH2CHRM1LMNA | |
| SCHEMBL10524246 | 0.66 | CHRM3 (0.57) | CHRM3CHRM2KCNH2CHRM1LMNA | |
| SCHEMBL4758054 | 0.66 | CHRM3 (0.49) | CHRM3CHRM2KCNH2CHRM1LMNA | |
| Hydrochloric Acid SCHEMBL8879883 | 0.66 | KMT2A (0.49) | CHRM3CHRM2KCNH2CHRM1LMNA | |
| SCHEMBL2984162 | 0.66 | CHRM3 (0.56) | CHRM3CHRM2KCNH2CHRM1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1020449-A1 | IMIDAZOLINE COMPOUNDS | Mitsubishi-Tokyo Pharmaceuticals, Inc. (JP) | 2000-07-19 | — | — | EP | claimed |
| EP-1020449-A1 | IMIDAZOLINE COMPOUNDS | Mitsubishi-Tokyo Pharmaceuticals, Inc. (JP) | 2000-07-19 | — | — | EP | disclosed |