Dimethylamine

Dimethylamine

SCHEMBL8071368

CCCCN1CCN(C)CC1.CNC

nearest known ligand 0.50

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Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
GNAI3 P08754 3/20 0.47
GNAO1 P09471 3/20 0.47
GNAI1 P63096 3/20 0.47
PAOX Q6QHF9 1/20 0.44
USP2 O75604 1/20 0.42
SIGMAR1 Q99720 2/20 0.41
TLR8 Q9NR97 1/20 0.41
TLR7 Q9NYK1 1/20 0.41
CSNK2A2 P19784 1/20 0.39
CSNK2B P67870 1/20 0.39
CSNK2A1 P68400 1/20 0.39
CSNK2A3 Q8NEV1 1/20 0.39
GLB1 P16278 1/20 0.39
DRD2 P14416 1/20 0.39
DRD3 P35462 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL240855 0.93 GNAI3 (0.52) GNAI3GNAO1GNAI1PAOXUSP2
Ammonia Solution, Strong SCHEMBL27751181 0.90 GNAI3 (0.50) GNAI3GNAO1GNAI1PAOXUSP2
SCHEMBL28860188 0.88 GNAI3 (0.48) GNAI3GNAO1GNAI1PAOXUSP2
Hydrochloric Acid SCHEMBL27751184 0.88 GNAI3 (0.54) GNAI3GNAO1GNAI1PAOXSIGMAR1
SCHEMBL23767406 0.85 GNAI3 (0.61) GNAI3GNAO1GNAI1PAOXSIGMAR1
SCHEMBL107589 0.85 GNAI3 (0.61) GNAI3GNAO1GNAI1PAOXSIGMAR1
SCHEMBL1537447 0.84
SCHEMBL18538874 0.84 GNAI3 (0.58) GNAI3GNAO1GNAI1SIGMAR1GLB1
SCHEMBL1043894 0.84 GNAI3 (0.58) GNAI3GNAO1GNAI1SIGMAR1GLB1
SCHEMBL2318272 0.84 GNAI3 (0.58) GNAI3GNAO1GNAI1SIGMAR1GLB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6063824-A CHAIN EXTENDERS AND CROSSLINKERS WITH BLOWING AGENTS AND ACIDS BASF AKTIENGESELLSCHAFT (DE) 2000-05-16 US disclosed
US-6037383-A P,P*-DIPHENYLMETHANE DIISOCYANATE MONOMER; DYNAMIC CONSOLIDATION VALUES, STATIC MECHANICAL PROPERTIES; RESILIENCE BASF AKTIENGESELLSCHAFT (DE) 2000-03-14 US disclosed