Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNAI3 | P08754 | 3/20 | 0.52 |
| ▸ | GNAO1 | P09471 | 3/20 | 0.52 |
| ▸ | GNAI1 | P63096 | 3/20 | 0.52 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.45 |
| ▸ | GLB1 | P16278 | 1/20 | 0.43 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.42 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.42 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.42 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL27751181 | 0.97 | GNAI3 (0.50) | GNAI3GNAO1GNAI1PAOXSIGMAR1 | |
| Hydrochloric Acid SCHEMBL27751184 | 0.95 | GNAI3 (0.54) | GNAI3GNAO1GNAI1PAOXSIGMAR1 | |
| SCHEMBL28860188 | 0.95 | GNAI3 (0.48) | GNAI3GNAO1GNAI1PAOXSIGMAR1 | |
| Dimethylamine SCHEMBL8071368 | 0.93 | GNAI3 (0.47) | GNAI3GNAO1GNAI1PAOXSIGMAR1 | |
| SCHEMBL23767406 | 0.92 | GNAI3 (0.61) | GNAI3GNAO1GNAI1PAOXSIGMAR1 | |
| SCHEMBL107589 | 0.92 | GNAI3 (0.61) | GNAI3GNAO1GNAI1PAOXSIGMAR1 | |
| SCHEMBL18538874 | 0.91 | GNAI3 (0.58) | GNAI3GNAO1GNAI1SIGMAR1GLB1 | |
| SCHEMBL1537447 | 0.91 | — | — | |
| SCHEMBL1043894 | 0.91 | GNAI3 (0.58) | GNAI3GNAO1GNAI1SIGMAR1GLB1 | |
| SCHEMBL2318272 | 0.91 | GNAI3 (0.58) | GNAI3GNAO1GNAI1SIGMAR1GLB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 602 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110269737-A1 | 7-(Piperazine-1-Ymethyl)-1H-Indole-2-Carboxylic Acid (Phenyl)-Amide Derivatives and Allied Compounds as P38 Map Kinase Inhibitors for the Treatment of Respiratory Diseases | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2011-11-03 | — | — | US | claimed |
| EP-1237935-A1 | MODIFIED POLYMERS PREPARED WITH LANTHANIDE-BASED CATALYSTS | Bridgestone Corporation (JP) | 2002-09-11 | — | — | EP | claimed |
| WO-2001034659-A1 | MODIFIED POLYMERS PREPARED WITH LANTHANIDE-BASED CATALYSTS | BRIDGESTONE CORPORATION (JP) | 2001-05-17 | — | — | WO | claimed |
| US-20240239804-A1 | FUROINDAZOLE DERIVATIVES AS ANTAGONISTS OR INHIBITORS OF GPR84 | BAYER AKTIENGESELLSCHAFT (DE) | 2024-07-18 | — | — | US | disclosed |
| US-20240228493-A1 | LRRK2 INHIBITORS AND USES THEREOF | NEURON23, INC. | 2024-07-11 | — | — | US | disclosed |
| US-12030985-B2 | Poly(amine-co-ester) polymers and polyplexes with modified end groups and methods of use thereof | YALE UNIVERSITY (US) | 2024-07-09 | — | — | US | disclosed |
| US-12030985-B2 | Poly(amine-co-ester) polymers and polyplexes with modified end groups and methods of use thereof | YALE UNIVERSITY (US) | 2024-07-09 | — | — | US | disclosed |
| EP-4393921-A1 | NALIDINONE COMPOUND AS FGFR4 INHIBITOR AND USE THEREOF | Wenzhou Medical University (CN) | 2024-07-03 | — | — | EP | disclosed |
| US-12024486-B2 | Lipocationic dendrimers and uses thereof | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2024-07-02 | — | — | US | disclosed |
| US-20240025848-A1 | LIPOCATIONIC DENDRIMERS AND USES THEREOF | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2024-01-25 | — | — | US | disclosed |
| EP-4309674-A1 | IONIZABLE CATIONIC LIPID ANALOGUE MATERIAL AND USE THEREOF AS DRUG DELIVERY CARRIER | Guangzhou Lide Biomedicine Technology Co., Ltd. (CN) | 2024-01-24 | — | — | EP | disclosed |
| US-20070043057-A1 | Lonidamine analogs | THRESHOLD PHARMACEUTICALS, INC. (US) | 2007-02-22 | — | — | US | disclosed |
| US-20070037834-A1 | Anti-inflammatory; cellular infiltration inhibition modulating activity on thymus and activation-regulated chemokine and macrophage-derived chemokine functions; inhibitory activities against binding of TARC and MDC to T cells; allergic disease, autoimmune disease, transplant, graft rejection | KYOWA HAKKO KIRIN CO., LTD. (JP) | 2007-02-15 | — | — | US | disclosed |
| EP-1562944-B1 | PYRAZOLOQUINOLINES WITH IMMUNOMODULATING ACTIVITY | ACTIVE BIOTECH AB (SE) | 2007-02-14 | — | — | EP | disclosed |
| US-20070032490-A1 | N-Phenyl-'(4-pyridyl)-azinyl!amine derivatives as plant protection agents | SYNGENTA CROP PROTECTION, INC. | 2007-02-08 | — | — | US | disclosed |
| WO-2005090291-A1 | ION CHANNEL MODULATORS | WYETH (US) | 2005-09-29 | — | — | WO | disclosed |
| WO-2005058874-A1 | 5- OR 6-SUBSTITUTED BENZIMIDAZOLE DERIVATIVES AS INHIBITORS OF RESPIRATORY SYNCYTIAL VIRUS REPLICATION | TIBOTEC PHARMACEUTICALS LTD. (IE) | 2005-06-30 | — | — | WO | disclosed |
| WO-2004073614-A2 | COMBINATION THERAPY FOR THE TREATMENT OF IMMUNOINFLAMMATORY DISORDERS | COMBINATORX, INCORPORATED (US) | 2004-09-02 | — | — | WO | disclosed |
| US-4992150-A | Telomer with alpha-olefin;oil and fuel additive | NIPPON OIL CO, LTD. (JP) | 1991-02-12 | — | — | US | disclosed |
| US-3992456-A | BY REACTING BUTADIENE WITH WATER IN THE PRESENCE OF A PALLADIUM CATALYST | UNION CARBIDE CORPORATION (US) | 1976-11-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110269737-A1 | 7-(Piperazine-1-Ymethyl)-1H-Indole-2-Carboxylic Acid (Phenyl)-Amide Derivatives and Allied Compounds as P38 Map Kinase Inhibitors for the Treatment of Respiratory Diseases | MAPKAPK2, MAPKAPK5, MAPK7 | GNAI3 368/4885GNAO1 962/4885GNAI1 240/4885 |
| US-20240025848-A1 | LIPOCATIONIC DENDRIMERS AND USES THEREOF | LIPA, LIPC, TLR9 | GNAI3 1032/4885GNAO1 1680/4885GNAI1 990/4885 |
| US-12030985-B2 | Poly(amine-co-ester) polymers and polyplexes with modified end groups and methods of use thereof | POLM, PARG, PARN | GNAI3 3419/4885GNAO1 2580/4885GNAI1 3798/4885 |
| US-12024486-B2 | Lipocationic dendrimers and uses thereof | LIPA, LIPC, TLR9 | GNAI3 1032/4885GNAO1 1680/4885GNAI1 990/4885 |
| US-20070032490-A1 | N-Phenyl-'(4-pyridyl)-azinyl!amine derivatives as plant protection agents | CYP1A1, NAT1, AKR7A2 | GNAI3 2398/4885GNAO1 1670/4885GNAI1 1697/4885 |
| US-20070043057-A1 | Lonidamine analogs | LONP1, LPXN, QDPR | GNAI3 2369/4885GNAO1 1975/4885GNAI1 2095/4885 |
| US-20070037834-A1 | Anti-inflammatory; cellular infiltration inhibition modulating activity on thymus and activation-regulated chemokine and macrophage-derived chemokine functions; inhibitory activities against binding of TARC and MDC to T cells; allergic disease, autoimmune disease, transplant, graft rejection | CX3CR1, CCL5, CCRL2 | GNAI3 2674/4885GNAO1 3166/4885GNAI1 3149/4885 |
| US-20240228493-A1 | LRRK2 INHIBITORS AND USES THEREOF | LRRK2, PINK1, PARK7 | GNAI3 135/4885GNAO1 765/4885GNAI1 132/4885 |
| US-20240239804-A1 | FUROINDAZOLE DERIVATIVES AS ANTAGONISTS OR INHIBITORS OF GPR84 | GPR84, GPR88, FFAR1 | GNAI3 1623/4885GNAO1 1474/4885GNAI1 1211/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.