Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8205710 | 0.80 | ALDH1A1 (0.30) | ALDH1A1LMNAHSD17B10 | |
| SCHEMBL8204239 | 0.76 | CYP4F2 (0.46) | ALDH1A1TRPA1LMNAHSD17B10 | |
| SCHEMBL800000 | 0.73 | ALDH1A1 (0.33) | ALDH1A1LMNAHSD17B10 | |
| SCHEMBL8217496 | 0.71 | — | — | |
| SCHEMBL17620031 | 0.70 | ALOX15 (0.33) | ALDH1A1 | |
| SCHEMBL19047429 | 0.69 | ALDH1A1 (0.42) | ALDH1A1TRPA1LMNAHSD17B10 | |
| SCHEMBL10064026 | 0.69 | ALDH1A1 (0.37) | ALDH1A1TRPA1LMNAHSD17B10 | |
| SCHEMBL9498044 | 0.68 | — | — | |
| SCHEMBL19023993 | 0.67 | — | — | |
| SCHEMBL7710774 | 0.67 | ALDH1A1 (0.48) | ALDH1A1TRPA1LMNAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009036055-A1 | VEGFR INHIBITORS CONTAINING A ZINC BINDING MOIETY | CURIS, INC. (US) | 2009-03-19 | — | — | WO | disclosed |