SCHEMBL8071725

SCHEMBL8071725

Cc1cccc(SSN)c1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 4/20 0.48
ALDH1A1 P00352 1/20 0.39
MAPK1 P28482 1/20 0.39
TAAR1 Q96RJ0 2/20 0.38
PARP1 P09874 1/20 0.38
IDO1 P14902 3/20 0.36
HTR3E A5X5Y0 1/20 0.36
HTR3B O95264 1/20 0.36
HTR3A P46098 1/20 0.36
HTR3D Q70Z44 1/20 0.36
HTR3C Q8WXA8 1/20 0.36
TP53 P04637 2/20 0.36
TDP1 Q9NUW8 2/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
CYP3A4 P08684 1/20 0.36
THRB P10828 1/20 0.36
ALOX15 P16050 1/20 0.36
DDB1 Q16531 1/20 0.36
CRBN Q96SW2 1/20 0.36
SCN2A Q99250 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL576105 0.85 ACHE (0.58) ACHEALDH1A1MAPK1PARP1IDO1
SCHEMBL29468620 0.85 ACHE (0.58) ACHEALDH1A1MAPK1PARP1IDO1
SCHEMBL11122557 0.81 ACHE (0.52) ACHEALDH1A1MAPK1PARP1IDO1
SCHEMBL11321246 0.81 ACHE (0.52) ACHEALDH1A1MAPK1PARP1IDO1
SCHEMBL5043777 0.81
SCHEMBL31325162 0.81
SCHEMBL11310830 0.79 ACHE (0.50) ACHEALDH1A1MAPK1PARP1IDO1
SCHEMBL3883625 0.79 HPGD (0.57) ACHEALDH1A1MAPK1HTR3ASMN1; SMN2
SCHEMBL3882269 0.79 ACHE (0.50) ACHEALDH1A1MAPK1PARP1IDO1
Fluoride SCHEMBL1635597 0.79 ACHE (0.50) ACHEALDH1A1MAPK1TAAR1PARP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0775696-B1 AMINO ACID AMIDE DERIVATIVE, PROCESS FOR PRODUCING THE SAME, AGROHORTICULTURAL FUNGICIDE, AND FUNGICIDAL METHOD KUMIAI CHEMICAL INDUSTRY CO (JP) 2000-07-19 EP disclosed
US-5789428-A Amino-acid amide derivatives, processes for preparing the same, agricultural or horticultural fungicides, and method for killing fungi KUMIAI CHEMICAL INDUSTRY CO. LTD. (JP) 1998-08-04 US disclosed
EP-0775696-A1 AMINO ACID AMIDE DERIVATIVE, PROCESS FOR PRODUCING THE SAME, AGROHORTICULTURAL FUNGICIDE, AND FUNGICIDAL METHOD KumaiI Chemical Industry Co., Ltd. (JP) 1997-05-28 EP disclosed