SCHEMBL576105

SCHEMBL576105

Cc1cccc(SSc2cccc(C)c2)c1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 5/20 0.58
ALDH1A1 P00352 1/20 0.46
MAPK1 P28482 1/20 0.46
HPGD P15428 2/20 0.43
HSD17B10 Q99714 2/20 0.43
MAPT P10636 2/20 0.43
CYP1A2 P05177 2/20 0.43
CYP2C9 P11712 2/20 0.43
SMN1; SMN2 Q16637 2/20 0.43
MGLL Q99685 1/20 0.43
HSP90AA1 P07900 1/20 0.41
TP53 P04637 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
DDB1 Q16531 1/20 0.40
CRBN Q96SW2 1/20 0.40
NPC1 O15118 1/20 0.39
CASP3 P42574 1/20 0.39
SENP8 Q96LD8 1/20 0.39
SENP7 Q9BQF6 1/20 0.39
SENP6 Q9GZR1 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29468620 1.00 ACHE (0.58) ACHEALDH1A1MAPK1HPGDHSD17B10
SCHEMBL3883625 0.93 HPGD (0.57) ACHEALDH1A1MAPK1HPGDHSD17B10
SCHEMBL2700337 0.91 ACHE (0.48) ACHEALDH1A1MAPK1HPGDHSD17B10
SCHEMBL11122557 0.90 ACHE (0.52) ACHEALDH1A1MAPK1HPGDHSD17B10
SCHEMBL11321246 0.90 ACHE (0.52) ACHEALDH1A1MAPK1HPGDHSD17B10
SCHEMBL11310830 0.87 ACHE (0.50) ACHEALDH1A1MAPK1HPGDHSD17B10
SCHEMBL3882269 0.87 ACHE (0.50) ACHEALDH1A1MAPK1HPGDHSD17B10
SCHEMBL22051340 0.87 ALDH1A1 (0.64) ACHEALDH1A1MAPK1HPGDHSD17B10
SCHEMBL19885312 0.87 ACHE (0.64) ACHEALDH1A1MAPK1HPGDHSD17B10
SCHEMBL26717446 0.87 ACHE (0.44) ACHEALDH1A1MAPK1HPGDHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 157 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5153305-A From diaryl disulfide; mild conditions using organometallic catalyst RESEARCH INSTITUTE FOR PRODUCTION DEVELOPMENT (JP) 1992-10-06 US claimed
US-12606675-B2 Sulfur-containing polymer, method for producing same, and sulfur-containing polymer composition NIPPON SHOKUBAI CO., LTD. (JP) 2026-04-21 US disclosed
US-12338327-B2 Polymeric material, production method therefor, and polymeric material composition NIPPON SHOKUBAI CO., LTD. (JP) 2025-06-24 US disclosed
US-20240297344-A1 NONAQUEOUS ELECTROLYTE FOR SECONDARY BATTERY AND NONAQUEOUS-ELECTROLYTE SECONDARY BATTERY EMPLOYING THE SAME MITSUBISHI CHEMICAL CORPORATION (JP) 2024-09-05 US disclosed
WO-2024128145-A1 SUBSTITUTED POLYPHENYLENE SULFIDE RESIN 株式会社ダイセル 2024-06-20 WO disclosed
EP-4361200-A1 METHOD FOR MANUFACTURING SULFUR-CONTAINING POLYMER Nippon Shokubai Co., Ltd. (JP) 2024-05-01 EP disclosed
US-20230357507-A1 SULFUR-CONTAINING POLYMER, METHOD FOR PRODUCING SAME, AND SULFUR-CONTAINING POLYMER COMPOSITION NIPPON SHOKUBAI CO., LTD. (JP) 2023-11-09 US disclosed
US-20230357507-A1 SULFUR-CONTAINING POLYMER, METHOD FOR PRODUCING SAME, AND SULFUR-CONTAINING POLYMER COMPOSITION NIPPON SHOKUBAI CO., LTD. (JP) 2023-11-09 US disclosed
US-20230357507-A1 SULFUR-CONTAINING POLYMER, METHOD FOR PRODUCING SAME, AND SULFUR-CONTAINING POLYMER COMPOSITION NIPPON SHOKUBAI CO., LTD. (JP) 2023-11-09 US disclosed
EP-4220242-A1 SULFUR-CONTAINING POLYMER, METHOD FOR PRODUCING SAME, AND SULFUR-CONTAINING POLYMER COMPOSITION Nippon Shokubai Co., Ltd. (JP) 2023-08-02 EP disclosed
EP-0402481-B1 PRODUCTION OF POLYARYLENE THIOETHER PROD DEV RES INST (JP) 1995-10-25 EP disclosed
US-5290911-A Forming polymers by catalytic oxidative coupling RESEARCH INSTITUTE FOR PRODUCTION DEVELOPMENT (JP) 1994-03-01 US disclosed
US-5153305-A From diaryl disulfide; mild conditions using organometallic catalyst RESEARCH INSTITUTE FOR PRODUCTION DEVELOPMENT (JP) 1992-10-06 US disclosed
EP-0402481-A1 PRODUCTION OF POLYARYLENE THIOETHER RESEARCH INSTITUTE FOR PRODUCTION DEVELOPMENT (JP) 1990-12-19 EP disclosed
US-4826851-A 2-substituted ergoline urea and thio-urea derivatives having neurolyptic/dopaminergic activity SCHERING AKTIENGESELLSCHAFT (DE) 1989-05-02 US disclosed
EP-0217735-A2 2-Substituted ergoline derivatives SCHERING AKTIENGESELLSCHAFT (DE) 1987-04-08 EP disclosed
US-4440893-A ETHYLENE HOMO OR COPOLYMER, IIA OR IIB OXIDE, AND ACETYLENE PEROXIDE COMPOUND PHILLIPS PETROLEUM COMPANY (US) 1984-04-03 US disclosed
US-4303765-A PEPTIZATION WITH AROMATIC POLYSULFIDE BAYER AKTIENGESELLSCHAFT (DE) 1981-12-01 US disclosed
US-4301063-A ETHYLENE HOMOPOLYMER AND COPOLYMERS UNION CARBIDE CORPORATION (US) 1981-11-17 US disclosed
US-3974114-A CALCIUM AND LITHIUM STEARATE UNION CARBIDE CORPORATION (US) 1976-08-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12606675-B2 Sulfur-containing polymer, method for producing same, and sulfur-containing polymer composition UACA, SMC3, SMC2 ACHE 4259/4885ALDH1A1 1086/4885MAPK1 1757/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.