Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALPL | P05186 | 1/20 | 0.49 |
| ▸ | PIK3CA | P42336 | 17/20 | 0.43 |
| ▸ | MTOR | P42345 | 11/20 | 0.43 |
| ▸ | PIK3R1 | P27986 | 4/20 | 0.43 |
| ▸ | PIK3CG | P48736 | 4/20 | 0.43 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.43 |
| ▸ | PIK3CB | P42338 | 3/20 | 0.43 |
| ▸ | PRF1 | P14222 | 1/20 | 0.42 |
| ▸ | PI4KA | P42356 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29434933 | 0.90 | ALPL (0.55) | ALPLPIK3CAMTORPIK3R1PIK3CG | |
| SCHEMBL110313 | 0.90 | ALPL (0.55) | ALPLPIK3CAMTORPIK3R1PIK3CG | |
| SCHEMBL29556110 | 0.90 | ALPL (0.55) | ALPLPIK3CAMTORPIK3R1PIK3CG | |
| SCHEMBL30333601 | 0.82 | ALPL (0.54) | ALPLPIK3CAMTORPIK3R1PIK3CG | |
| SCHEMBL18759850 | 0.82 | ALPL (0.54) | ALPLPIK3CAMTORPIK3R1PIK3CG | |
| SCHEMBL15559069 | 0.82 | ALPL (0.52) | ALPLPIK3CAMTORPIK3R1PIK3CG | |
| SCHEMBL22447700 | 0.81 | ALPL (0.52) | ALPLPIK3CAMTORPIK3R1PIK3CG | |
| SCHEMBL9953720 | 0.81 | ALPL (0.62) | ALPLPIK3CAMTORPIK3R1PIK3CG | |
| SCHEMBL798076 | 0.80 | ALPL (0.47) | ALPLPIK3CAMTORPIK3R1PIK3CG | |
| SCHEMBL15560224 | 0.80 | ALPL (0.58) | ALPLPIK3CAMTORPIK3R1PIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012037108-A1 | AMINOQUINOLINE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-03-22 | — | — | WO | disclosed |