Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALPL | P05186 | 1/20 | 0.47 |
| ▸ | PIK3CA | P42336 | 15/20 | 0.45 |
| ▸ | PIK3R1 | P27986 | 5/20 | 0.45 |
| ▸ | PIK3CG | P48736 | 3/20 | 0.44 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.44 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | MTOR | P42345 | 8/20 | 0.44 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | PI4KA | P42356 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22447713 | 0.90 | PIK3CA (0.47) | ALPLPIK3CAPIK3R1PIK3CGPIK3CD | |
| SCHEMBL110313 | 0.90 | ALPL (0.55) | ALPLPIK3CAPIK3R1PIK3CGPIK3CD | |
| SCHEMBL29556110 | 0.90 | ALPL (0.55) | ALPLPIK3CAPIK3R1PIK3CGPIK3CD | |
| SCHEMBL29434933 | 0.90 | ALPL (0.55) | ALPLPIK3CAPIK3R1PIK3CGPIK3CD | |
| SCHEMBL9953341 | 0.89 | ALPL (0.51) | ALPLPIK3CAPIK3R1PIK3CGPIK3CD | |
| SCHEMBL790655 | 0.85 | PIK3C3 (0.53) | PIK3CAMTOR | |
| SCHEMBL31029634 | 0.84 | BRD4 (0.47) | ALPLPIK3CDPIK3CBBRD4KDM4E | |
| SCHEMBL12276481 | 0.84 | PIK3CD (0.57) | ALPLPIK3CAPIK3CGPIK3CDPIK3CB | |
| SCHEMBL29556116 | 0.84 | PIK3CD (0.57) | ALPLPIK3CAPIK3CGPIK3CDPIK3CB | |
| SCHEMBL789981 | 0.82 | ALPL (0.48) | ALPLPIK3CAPIK3R1PIK3CGPIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012037108-A1 | AMINOQUINOLINE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-03-22 | — | — | WO | disclosed |