Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8389426 | 1.00 | TP53 (0.32) | TP53 | |
| SCHEMBL17662488 | 0.80 | NOS3 (0.33) | — | |
| SCHEMBL15645910 | 0.78 | — | — | |
| SCHEMBL7161276 | 0.67 | — | — | |
| SCHEMBL7161283 | 0.67 | — | — | |
| SCHEMBL9144010 | 0.65 | ALDH1A1 (0.33) | — | |
| SCHEMBL5145029 | 0.65 | ALDH1A1 (0.33) | — | |
| SCHEMBL10045204 | 0.65 | — | — | |
| SCHEMBL24187533 | 0.63 | ALDH1A1 (0.31) | — | |
| SCHEMBL1319847 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2046964-B1 | TRANSDUCIBLE DELIVERY OF NUCLEIC ACIDS BY REVERSIBLE PHOSPHOTRIESTER CHARGE NEUTRALIZATION PROTECTING GROUPS | UNIV CALIFORNIA (US) | 2018-07-04 | — | — | EP | claimed |
| US-6124445-A | PRO DRUGS FOR OLIGONUCLEOTIDES HAVING BIOREVERSIBLE PHOSPHATE BLOCKING GROUPS | ISIS PHARMACEUTICALS, INC. (US) | 2000-09-26 | — | — | US | disclosed |
| US-5955591-A | OLIGONUCLEOTIDES HAVING BIOREVERSIBLE PHOSPHATE BLOCKING GROUPS; USED AS PRODRUGS; ANTISENSE AGENTS | CENTER NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 1999-09-21 | — | — | US | disclosed |
| US-5627185-A | Acyclovir derivatives as antiviral agents | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 1997-05-06 | — | — | US | disclosed |
| WO-1996033201-A1 | ACYCLOVIR DERIVATIVES AS ANTIVIRAL AGENTS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 1996-10-24 | — | — | WO | disclosed |