SCHEMBL8072906

SCHEMBL8072906

C=C(C)C(=O)OCCl.CCP(CC)CC

nearest known ligand 0.48

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.48
THRB P10828 1/20 0.46
ALDH1A1 P00352 4/20 0.43
POLB P06746 1/20 0.31
APEX1 P27695 1/20 0.31
HTT P42858 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
LMNA P02545 1/20 0.30
HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1170947 0.87
SCHEMBL27585831 0.85
Butadiene SCHEMBL10807543 0.77 ALDH1A1 (0.56) TSHRTHRBALDH1A1
Methylene Chloride SCHEMBL28244287 0.74 THRB (0.57) TSHRTHRBALDH1A1LMNAHSD17B10
Acrylonitrile SCHEMBL28377276 0.73 TSHR (0.46) TSHRTHRBALDH1A1
SCHEMBL9435457 0.72 THRB (0.55) TSHRTHRBALDH1A1POLBAPEX1
Chloromethane SCHEMBL17453350 0.72 THRB (0.59) TSHRTHRBALDH1A1LMNAHSD17B10
SCHEMBL10862594 0.71 THRB (0.53) TSHRTHRBALDH1A1LMNAHSD17B10
SCHEMBL19409375 0.71 THRB (0.64) TSHRTHRBALDH1A1LMNAHSD17B10
SCHEMBL15030 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-2000007737-A WATER-SOLUBLE ANTIMICROBIAL HEAT-SENSITIVE RESIN AND FLOCCULANT NIPPON CHEM IND CO LTD 2000-01-11 JP disclosed