Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNE2 | O96020 | 1/20 | 0.55 |
| ▸ | CDK4 | P11802 | 1/20 | 0.55 |
| ▸ | CCND1 | P24385 | 1/20 | 0.55 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.55 |
| ▸ | CDK2 | P24941 | 1/20 | 0.55 |
| ▸ | PIM1 | P11309 | 2/20 | 0.54 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.54 |
| ▸ | PRKCA | P17252 | 1/20 | 0.52 |
| ▸ | PRKACA | P17612 | 1/20 | 0.52 |
| ▸ | PRKACG | P22612 | 1/20 | 0.52 |
| ▸ | PRKACB | P22694 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8065185 | 0.84 | PRKCA (0.68) | CCNE2CDK4CCND1CCNE1CDK2 | |
| SCHEMBL8072942 | 0.84 | CCNE2 (0.62) | CCNE2CDK4CCND1CCNE1CDK2 | |
| Hydrochloric Acid SCHEMBL8064918 | 0.83 | PRKCA (0.67) | CCNE2CDK4CCND1CCNE1CDK2 | |
| SCHEMBL8167903 | 0.82 | CCNE2 (0.72) | CCNE2CDK4CCND1CCNE1CDK2 | |
| SCHEMBL8065304 | 0.82 | PRKCA (0.64) | CCNE2CDK4CCND1CCNE1CDK2 | |
| Hydrochloric Acid SCHEMBL8064897 | 0.81 | PRKCB (0.58) | CCNE2CDK4CCND1CCNE1CDK2 | |
| SCHEMBL8161974 | 0.80 | PIM1 (0.69) | CCNE2CDK4CCND1CCNE1CDK2 | |
| SCHEMBL8080083 | 0.80 | PRKCA (0.59) | PIM1CAMK2DPRKCA | |
| SCHEMBL8317085 | 0.80 | PRKCA (0.59) | PIM1CAMK2DPRKCA | |
| SCHEMBL8654876 | 0.80 | CCNE2 (0.58) | CCNE2CDK4CCND1CCNE1CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6153641-A | Pharmaceutically active compounds | ASTRA AKTIEBOLAG (SE) | 2000-11-28 | — | — | US | disclosed |