Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.65 |
| ▸ | THRB | P10828 | 2/20 | 0.65 |
| ▸ | TAS2R14 | Q9NYV8 | 6/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | PTGES | O14684 | 1/20 | 0.48 |
| ▸ | TAS2R8 | Q9NYW2 | 1/20 | 0.48 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8083933 | 0.90 | MAPT (0.51) | MAPTTHRBTAS2R14PTGESCXCR3 | |
| SCHEMBL8074729 | 0.89 | TAS2R14 (0.56) | MAPTTHRBTAS2R14PTGESTAS2R8 | |
| SCHEMBL8074805 | 0.89 | MAPT (0.53) | MAPTTHRBTAS2R14CXCR3POLB | |
| SCHEMBL8069684 | 0.85 | TAS2R14 (0.65) | MAPTTAS2R14PTGESTAS2R8CXCR3 | |
| SCHEMBL8059119 | 0.84 | MAPT (0.59) | MAPTTAS2R14PTGESTAS2R8CXCR3 | |
| SCHEMBL8070323 | 0.83 | MAPT (0.52) | MAPTTAS2R14PTGESTAS2R8CXCR3 | |
| SCHEMBL8074725 | 0.83 | MAPT (0.63) | MAPTTHRBTAS2R14POLBTP53 | |
| SCHEMBL8073250 | 0.82 | TAS2R14 (0.61) | MAPTTAS2R14ALDH1A1PTGESTAS2R8 | |
| SCHEMBL8059346 | 0.82 | MAPT (0.51) | MAPTTAS2R14PTGESCXCR3POLB | |
| SCHEMBL8069963 | 0.82 | TAS2R14 (0.64) | MAPTTAS2R14PTGESTAS2R8CXCR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1017685-A1 | NEW 2-(3H)-OXAZOLONE DERIVATIVES | ALMIRALL-PRODESFARMA, S.A. (ES) | 2000-07-12 | — | — | EP | disclosed |
| WO-1999014205-A1 | NEW 2-(3H)-OXAZOLONE DERIVATIVES | ALMIRALL PRODESFARMA S.A. (ES) | 1999-03-25 | — | — | WO | disclosed |