Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | TAS2R14 | Q9NYV8 | 8/20 | 0.50 |
| ▸ | CXCR3 | P49682 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | PTGES | O14684 | 1/20 | 0.46 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.46 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.46 |
| ▸ | SPPL2A | Q8TCT8 | 1/20 | 0.46 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.46 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.46 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.46 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8074805 | 0.92 | MAPT (0.53) | MAPTTHRBTAS2R14CXCR3MEN1 | |
| SCHEMBL8073014 | 0.90 | MAPT (0.65) | MAPTTHRBTAS2R14CXCR3MEN1 | |
| SCHEMBL8070249 | 0.88 | MAPT (0.49) | MAPTTHRBTAS2R14CXCR3MEN1 | |
| SCHEMBL8059119 | 0.88 | MAPT (0.59) | MAPTTAS2R14CXCR3MEN1KMT2A | |
| SCHEMBL8070323 | 0.87 | MAPT (0.52) | MAPTTAS2R14CXCR3MEN1KMT2A | |
| SCHEMBL8059346 | 0.86 | MAPT (0.51) | MAPTTAS2R14CXCR3MEN1KMT2A | |
| SCHEMBL8073121 | 0.85 | MAPT (0.57) | MAPTTAS2R14CXCR3MEN1KMT2A | |
| SCHEMBL8074843 | 0.85 | TAS2R14 (0.55) | MAPTTAS2R14CXCR3MEN1KMT2A | |
| SCHEMBL8074725 | 0.85 | MAPT (0.63) | MAPTTHRBTAS2R14MEN1KMT2A | |
| SCHEMBL8073250 | 0.84 | TAS2R14 (0.61) | MAPTTAS2R14CXCR3MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0888316-B1 | 2-(3H)-OXAZOLONE DERIVATIVES AND THEIR USE AS COX-2 INHIBITORS | ALMIRALL PRODESFARMA SA (ES) | 2000-11-02 | — | — | EP | disclosed |