Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 4/20 | 0.59 |
| ▸ | GSK3B | P49841 | 6/20 | 0.58 |
| ▸ | FLT3 | P36888 | 3/20 | 0.58 |
| ▸ | PRKCA | P17252 | 3/20 | 0.56 |
| ▸ | CCNE2 | O96020 | 2/20 | 0.56 |
| ▸ | CDK4 | P11802 | 2/20 | 0.56 |
| ▸ | CCND1 | P24385 | 2/20 | 0.56 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.56 |
| ▸ | CDK2 | P24941 | 2/20 | 0.56 |
| ▸ | PIM1 | P11309 | 1/20 | 0.53 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8073079 | 0.92 | GSK3B (0.58) | KDRGSK3BFLT3PRKCACCNE2 | |
| SCHEMBL8064917 | 0.88 | GSK3B (0.58) | KDRGSK3BFLT3PRKCACCNE2 | |
| SCHEMBL8064786 | 0.83 | GSK3B (0.59) | KDRGSK3BFLT3PRKCACCNE2 | |
| SCHEMBL8073838 | 0.78 | CCNE2 (0.66) | GSK3BPRKCACCNE2CDK4CCND1 | |
| Hydrochloric Acid SCHEMBL8075396 | 0.77 | PRKCA (0.59) | KDRGSK3BFLT3PRKCAPIM1 | |
| SCHEMBL8161322 | 0.76 | CCNE2 (0.74) | GSK3BPRKCACCNE2CDK4CCND1 | |
| SCHEMBL8072942 | 0.75 | CCNE2 (0.62) | GSK3BPRKCACCNE2CDK4CCND1 | |
| SCHEMBL8075578 | 0.75 | CCNE2 (0.62) | GSK3BPRKCACCNE2CDK4CCND1 | |
| SCHEMBL8167903 | 0.75 | CCNE2 (0.72) | GSK3BPRKCACCNE2CDK4CCND1 | |
| SCHEMBL1155542 | 0.75 | KDR (1.00) | KDRGSK3BFLT3PRKCACCNE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6153641-A | Pharmaceutically active compounds | ASTRA AKTIEBOLAG (SE) | 2000-11-28 | — | — | US | disclosed |