Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 7/20 | 0.58 |
| ▸ | KDR | P35968 | 5/20 | 0.58 |
| ▸ | FLT3 | P36888 | 3/20 | 0.58 |
| ▸ | PIM1 | P11309 | 1/20 | 0.57 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.57 |
| ▸ | PRKCA | P17252 | 3/20 | 0.56 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.53 |
| ▸ | CDK4 | P11802 | 1/20 | 0.53 |
| ▸ | CCND1 | P24385 | 1/20 | 0.53 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.53 |
| ▸ | CDK2 | P24941 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8064917 | 0.93 | GSK3B (0.58) | GSK3BKDRFLT3PIM1CAMK2D | |
| SCHEMBL8073162 | 0.92 | KDR (0.59) | GSK3BKDRFLT3PIM1CAMK2D | |
| Hydrochloric Acid SCHEMBL8075396 | 0.82 | PRKCA (0.59) | GSK3BKDRFLT3PIM1CAMK2D | |
| SCHEMBL8075731 | 0.81 | PIM1 (0.70) | PIM1CAMK2DPRKCACCNE2CDK4 | |
| SCHEMBL8075459 | 0.77 | PIM1 (0.70) | PIM1CAMK2DPRKCACCNE2CDK4 | |
| SCHEMBL8064786 | 0.77 | GSK3B (0.59) | GSK3BKDRFLT3PIM1CAMK2D | |
| SCHEMBL8073168 | 0.77 | PRKCA (0.58) | GSK3BKDRPIM1CAMK2DPRKCA | |
| SCHEMBL8075976 | 0.77 | PIM1 (0.60) | PIM1CAMK2DPRKCACCNE2CDK4 | |
| Hydrochloric Acid SCHEMBL8079978 | 0.76 | PIM1 (0.59) | PIM1CAMK2DPRKCACCNE2CDK4 | |
| Hydrochloric Acid SCHEMBL8163206 | 0.76 | PIM1 (0.86) | GSK3BPIM1CAMK2DPRKCACCNE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6153641-A | Pharmaceutically active compounds | ASTRA AKTIEBOLAG (SE) | 2000-11-28 | — | — | US | disclosed |