Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNT1 | O60563 | 2/20 | 0.47 |
| ▸ | CDK9 | P50750 | 2/20 | 0.47 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.46 |
| ▸ | PIM1 | P11309 | 2/20 | 0.44 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.44 |
| ▸ | CCNE2 | O96020 | 2/20 | 0.43 |
| ▸ | CDK4 | P11802 | 2/20 | 0.43 |
| ▸ | CCND1 | P24385 | 2/20 | 0.43 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.43 |
| ▸ | CDK2 | P24941 | 2/20 | 0.43 |
| ▸ | PRKCA | P17252 | 1/20 | 0.43 |
| ▸ | PRKACA | P17612 | 1/20 | 0.43 |
| ▸ | PRKACG | P22612 | 1/20 | 0.43 |
| ▸ | PRKACB | P22694 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8079796 | 0.78 | PIM1 (0.65) | PIM1CAMK2DCCNE2CDK4CCND1 | |
| Hydrochloric Acid SCHEMBL8319144 | 0.77 | PIM1 (0.64) | PIM1CAMK2DCCNE2CDK4CCND1 | |
| SCHEMBL3155154 | 0.76 | CCNT1 (0.58) | CCNT1CDK9PIM1CAMK2DCCNE2 | |
| SCHEMBL8075637 | 0.76 | CCNT1 (0.50) | CCNT1CDK9SIRT2PIM1CAMK2D | |
| SCHEMBL8161267 | 0.74 | CDK2 (0.56) | CCNT1CDK9CCNE2CDK4CCND1 | |
| SCHEMBL30834692 | 0.74 | CCNT1 (0.56) | CCNT1CDK9SIRT2PIM1CAMK2D | |
| SCHEMBL8166629 | 0.74 | PIM1 (0.59) | CCNT1CDK9SIRT2PIM1CAMK2D | |
| SCHEMBL8161831 | 0.73 | CCNT1 (0.64) | CCNT1CDK9PIM1CAMK2DCDK2 | |
| SCHEMBL27868039 | 0.71 | SIRT2 (0.66) | CCNT1CDK9SIRT2 | |
| SCHEMBL8073012 | 0.71 | SIRT2 (0.47) | CCNT1CDK9SIRT2PIM1CAMK2D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6153641-A | Pharmaceutically active compounds | ASTRA AKTIEBOLAG (SE) | 2000-11-28 | — | — | US | disclosed |