Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.38 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8066750 | 0.93 | PKM (0.42) | PKMUCHL1KDM4EHSD17B10HPGD | |
| SCHEMBL8066995 | 0.88 | HSD17B10 (0.47) | UCHL1KDM4EHSD17B10HPGDALDH1A1 | |
| SCHEMBL5513825 | 0.88 | UCHL1 (0.45) | UCHL1KDM4EHSD17B10HPGDALDH1A1 | |
| SCHEMBL7824695 | 0.86 | UCHL1 (0.44) | UCHL1KDM4EHSD17B10HPGDALDH1A1 | |
| SCHEMBL7822518 | 0.84 | HPGD (0.50) | UCHL1KDM4EHPGDALDH1A1MAPT | |
| SCHEMBL7830785 | 0.84 | UCHL1 (0.46) | UCHL1KDM4EHSD17B10HPGDALDH1A1 | |
| SCHEMBL8073814 | 0.83 | UCHL1 (0.41) | UCHL1KDM4EHSD17B10HPGDALDH1A1 | |
| SCHEMBL5512013 | 0.83 | UCHL1 (0.41) | UCHL1KDM4EHSD17B10HPGDALDH1A1 | |
| SCHEMBL7822742 | 0.83 | SMN1; SMN2 (0.43) | UCHL1KDM4EHSD17B10HPGDALDH1A1 | |
| SCHEMBL8068094 | 0.83 | UCHL1 (0.42) | UCHL1KDM4EHSD17B10HPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6093714-A | AN ANTIALLERGENS FOR TREATMENT AND PREVENTION OF BRONCHIAL ASTHMA, ECZEMA, HIVES, ALLERGIC GASTROINTESTINAL TROUBLES, ALLERGIC RHINITIS, ALLERGIC CONJUNCTIVITIS | MEIJI SEIKA KAISHA, LTD. (JP) | 2000-07-25 | — | — | US | disclosed |
| EP-0834512-A1 | TRICYCLIC BENZAZEPINE COMPOUNDS | MEIJI SEIKA KAISHA LTD. (JP) | 1998-04-08 | — | — | EP | disclosed |