Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17574065 | 0.88 | DGAT1 (0.44) | DGAT1RECQL | |
| SCHEMBL12339113 | 0.83 | TSHR (0.32) | — | |
| SCHEMBL8209867 | 0.79 | DGAT1 (0.38) | DGAT1 | |
| SCHEMBL13254841 | 0.78 | DGAT1 (0.34) | DGAT1 | |
| SCHEMBL19867008 | 0.78 | CYP4F2 (0.47) | — | |
| SCHEMBL786780 | 0.78 | DGAT1 (0.41) | DGAT1 | |
| SCHEMBL23131222 | 0.77 | DGAT1 (0.37) | DGAT1 | |
| SCHEMBL22105978 | 0.77 | DGAT1 (0.58) | DGAT1 | |
| SCHEMBL1305303 | 0.77 | DGAT1 (0.37) | DGAT1 | |
| SCHEMBL12690948 | 0.76 | DGAT1 (0.39) | DGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009036051-A1 | BCL-2 INHIBITORS CONTAINING A ZINC BINDING MOIETY | CURIS, INC. (US) | 2009-03-19 | — | — | WO | disclosed |
| WO-2008033747-A9 | MULTI-FUNCTIONAL SMALL MOLECULES AS ANTI-PROLIFERATIVE AGENTS | CURIS INC (MA) | 2008-07-24 | — | — | WO | disclosed |
| WO-2008033749-A2 | QUINAZOLINE BASED EGFR INHIBITORS CONTAINING A ZINC BINDING MOIETY | CURIS, INC. (US) | 2008-03-20 | — | — | WO | disclosed |
| WO-2008033744-A2 | DNA METHYL TRANSFERASE INHIBITORS CONTAINING A ZINC BINDING MOIETY | CURIS, INC. (US) | 2008-03-20 | — | — | WO | disclosed |
| WO-2008033747-A2 | MULTI-FUNCTIONAL SMALL MOLECULES AS ANTI-PROLIFERATIVE AGENTS | CURIS, INC. (US) | 2008-03-20 | — | — | WO | disclosed |