SCHEMBL786780

SCHEMBL786780

COC(=O)C(C)(C)CC(C)(C)C

nearest known ligand 0.41

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
DGAT1 O75907 1/20 0.41
TSHR P16473 3/20 0.33
KCNN4 O15554 1/20 0.32
ALDH1A1 P00352 1/20 0.32
POLB P06746 1/20 0.31
HSD17B10 Q99714 1/20 0.31
MGAM O43451 1/20 0.31
GAA P10253 1/20 0.31
SI P14410 1/20 0.31
MGAM2 Q2M2H8 1/20 0.31
TET2 Q6N021 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17574065 0.89 DGAT1 (0.44) DGAT1TSHRKCNN4ALDH1A1HSD17B10
SCHEMBL17124363 0.82 DGAT1 (0.39) DGAT1TSHRKCNN4ALDH1A1
SCHEMBL10078130 0.82 DGAT1 (0.39) DGAT1TSHRKCNN4ALDH1A1
SCHEMBL12690945 0.82 DGAT1 (0.39) DGAT1TSHRKCNN4ALDH1A1
SCHEMBL12690948 0.82 DGAT1 (0.39) DGAT1TSHRKCNN4ALDH1A1
SCHEMBL10093742 0.82 DGAT1 (0.39) DGAT1TSHRKCNN4ALDH1A1
SCHEMBL10027501 0.82 DGAT1 (0.39) DGAT1TSHRKCNN4ALDH1A1
SCHEMBL16807263 0.82 DGAT1 (0.39) DGAT1TSHRKCNN4ALDH1A1
SCHEMBL28447095 0.81
SCHEMBL12449512 0.81 PRSS1 (0.37) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109721448-B Method for preparing alkyl derivative by liquid-phase oxidative carbonylation of methyl tert-butyl ether 河北工业大学 2021-06-08 CN claimed
US-6818049-B1 HALOGEN FREE INDUSTRIAL SOLVENT FORMULATION; LOW REACTIVITY TO OZONE FORMATION EXXONMOBIL CHEMICAL PATENTS INC. 2004-11-16 US claimed
US-6506243-B1 Industrial solvents; dialkyl carbonates, alkyl acetates, dioxolanes, pivalates, isobutyrates, nitriles EXXONMOBIL CHEMICAL PATENTS INC. 2003-01-14 US claimed
WO-2002064687-A1 ENVIRONMENTALLY PREFERRED FLUIDS AND FLUID BLENDS EXXONMOBIL CHEMICAL PATENTS INC. (US) 2002-08-22 WO claimed
EP-1090085-A1 ENVIRONMENTALLY PREFERRED FLUIDS AND FLUID BLENDS EXXON CHEMICAL PATENTS INC. (US) 2001-04-11 EP claimed
WO-1999057217-A1 ENVIRONMENTALLY PREFERRED FLUIDS AND FLUID BLENDS EXXON CHEMICAL PATENTS INC. (US) 1999-11-11 WO claimed
CN-110605145-B Catalyst for methyl hydrogen esterification reaction and method for preparing isononanoic acid 万华化学集团股份有限公司 2022-04-22 CN disclosed
CN-109721448-B Method for preparing alkyl derivative by liquid-phase oxidative carbonylation of methyl tert-butyl ether 河北工业大学 2021-06-08 CN disclosed
EP-2654794-B1 MATERIALS AND METHODS FOR CONJUGATING A WATER SOLUBLE FATTY ACID DERIVATIVE TO A PROTEIN Baxalta GmbH (CH) 2020-03-04 EP disclosed
CN-110605145-A Catalyst for methyl hydrogen esterification reaction and method for preparing isononanoic acid 万华化学集团股份有限公司 2019-12-24 CN disclosed
EP-2902212-B1 IMAGE FORMATION METHOD FUJIFILM CORP (JP) 2017-09-06 EP disclosed
US-20170210734-A1 Substituted Azaspiro(4.5)Decane Derivatives GRUENENTHAL GMBH (DE) 2017-07-27 US disclosed
US-9291893-B2 Resist composition and method for producing resist pattern SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2016-03-22 US disclosed
WO-2002064687-A1 ENVIRONMENTALLY PREFERRED FLUIDS AND FLUID BLENDS EXXONMOBIL CHEMICAL PATENTS INC. (US) 2002-08-22 WO disclosed
US-20020002933-A1 Environmentally preferred fluids and fluid blends YEZRIELEV ALBERT ILYA (US) 2002-01-10 US disclosed
US-20010041808-A1 Production of esters EXXONMOBIL CHEMICAL PATENTS INC. 2001-11-15 US disclosed
US-6280519-B1 Environmentally preferred fluids and fluid blends EXXON CHEMICAL PATENTS INC. 2001-08-28 US disclosed
WO-2001047861-A1 PRODUCTION OF ESTERS EXXONMOBIL CHEMICAL PATENTS INC. (US) 2001-07-05 WO disclosed
EP-1090085-A1 ENVIRONMENTALLY PREFERRED FLUIDS AND FLUID BLENDS EXXON CHEMICAL PATENTS INC. (US) 2001-04-11 EP disclosed
WO-1999057217-A1 ENVIRONMENTALLY PREFERRED FLUIDS AND FLUID BLENDS EXXON CHEMICAL PATENTS INC. (US) 1999-11-11 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170210734-A1 Substituted Azaspiro(4.5)Decane Derivatives OPRL1, OPRM1, OPRD1 DGAT1 2614/4885TSHR 1767/4885KCNN4 2070/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.