SCHEMBL8073528

SCHEMBL8073528

C=C(C)N(c1ccccc1)c1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 3/20 0.50
ALDH1A1 P00352 4/20 0.46
KMT2A Q03164 5/20 0.44
MEN1 O00255 4/20 0.44
L3MBTL1 Q9Y468 2/20 0.44
GAA P10253 1/20 0.44
MAPT P10636 1/20 0.44
HPGD P15428 1/20 0.44
NPC1 O15118 2/20 0.41
HTT P42858 2/20 0.41
POLB P06746 1/20 0.41
RAB9A P51151 1/20 0.41
ATM Q13315 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
TSHR P16473 2/20 0.39
APAF1 O14727 1/20 0.38
TRPM8 Q7Z2W7 2/20 0.38
FAAH O00519 1/20 0.37
PHGDH O43175 1/20 0.37
MGLL Q99685 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22052880 0.86 MAPT (0.43) NPSR1ALDH1A1KMT2AMEN1MAPT
SCHEMBL11168711 0.79 MEN1 (0.40) NPSR1ALDH1A1KMT2AMEN1L3MBTL1
SCHEMBL22135626 0.77 HPGD (0.40) NPSR1ALDH1A1KMT2AMEN1L3MBTL1
SCHEMBL14217912 0.77 FAAH (0.50) KMT2AMEN1L3MBTL1NPC1HTT
SCHEMBL195179 0.77 NPSR1 (0.54) NPSR1ALDH1A1KMT2AMEN1L3MBTL1
SCHEMBL11252920 0.77 ALDH1A1 (0.50) NPSR1ALDH1A1KMT2AMEN1L3MBTL1
SCHEMBL11463050 0.75 MEN1 (0.38) NPSR1ALDH1A1KMT2AMEN1L3MBTL1
SCHEMBL741752 0.74 NPSR1 (0.64) NPSR1ALDH1A1KMT2AMEN1L3MBTL1
SCHEMBL9743840 0.74 ALDH1A1 (0.58) NPSR1ALDH1A1KMT2AMEN1L3MBTL1
SCHEMBL7521817 0.74 ALDH1A1 (0.58) NPSR1ALDH1A1KMT2AMEN1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3764416-A1 COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT USING THE SAME, AND AN ELECTRONIC DEVICE THEREOF Duk San Neolux Co., Ltd. (KR) 2021-01-13 EP disclosed
EP-3235799-A1 KETONE OR OXIME COMPOUND, AND HERBICIDE Nissan Chemical Industries, Ltd. (JP) 2017-10-25 EP disclosed
US-20130226549-A1 STRUCTURE-BASED FRAGMENT HOPPING FOR LEAD OPTIMIZATION AND IMPROVEMENT IN SYNTHETIC ACCESSIBILITY TSENG, YUFENG J. (TW) 2013-08-29 US disclosed
US-6033819-A FIXABLE COMPONENT HAS A MICRO PHASE SEPARATION STRUCTURE OF A LIQUID CONTINUOUS PHASE AND A DISPERSE PHASE CONTAINING A RESIN AND HAVING A GLASS TRANSITION TEMPERATURE OF NOT HIGHER THAN 20 DEGREES, CONTAINING A BLOCK OR GRAFT POLYMER FUJI XEROX CO., LTD. (JP) 2000-03-07 US disclosed
US-3944492-A Lubricant compositions containing N-substituted naphthylamines as antioxidants UNIROYAL, INC. (US) 1976-03-16 US disclosed