Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 3/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.39 |
| ▸ | GABRR2 | P28476 | 2/20 | 0.39 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | GABRP | O00591 | 2/20 | 0.37 |
| ▸ | GABRD | O14764 | 2/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.37 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.37 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.37 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.37 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.37 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.37 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7078093 | 1.00 | KDM1A (0.43) | KDM1ABLMPTPN1GABRR1GABRR2 | |
| SCHEMBL3814942 | 0.94 | KDM1A (0.42) | KDM1ABLMPTPN1GABRR1GABRR2 | |
| SCHEMBL3814938 | 0.94 | KDM1A (0.42) | KDM1ABLMPTPN1GABRR1GABRR2 | |
| SCHEMBL5654019 | 0.92 | PTPN1 (0.45) | KDM1ABLMPTPN1TBXAS1ALDH1A1 | |
| SCHEMBL1740084 | 0.92 | PTPN1 (0.45) | KDM1ABLMPTPN1TBXAS1ALDH1A1 | |
| SCHEMBL23924379 | 0.92 | PTPN1 (0.45) | KDM1ABLMPTPN1TBXAS1ALDH1A1 | |
| SCHEMBL9751266 | 0.92 | PTPN1 (0.45) | KDM1ABLMPTPN1TBXAS1ALDH1A1 | |
| SCHEMBL5654028 | 0.92 | PTPN1 (0.45) | KDM1ABLMPTPN1TBXAS1ALDH1A1 | |
| SCHEMBL22555602 | 0.92 | PTPN1 (0.45) | KDM1ABLMPTPN1TBXAS1ALDH1A1 | |
| SCHEMBL23924669 | 0.92 | PTPN1 (0.45) | KDM1ABLMPTPN1TBXAS1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6020371-A | VIRICIDES; PROTEASE INHIBITORS | AGOURON PHARMACEUTICALS, INC. (US) | 2000-02-01 | — | — | US | disclosed |