Sugi Predict

Sugi Predict / Compounds / SCHEMBL3814938

SCHEMBL3814938

SCHEMBL3814938

CC(C)CCCC/C=C/C(=O)O

nearest known ligand 0.61

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ KDM1A O60341 1/20 0.42
▸ PTPN1 P18031 1/20 0.42
▸ ALDH1A1 P00352 1/20 0.42
▸ MAPT P10636 1/20 0.42
▸ BLM P54132 3/20 0.39
▸ TBXAS1 P24557 3/20 0.39
▸ GABRR1 P24046 2/20 0.38
▸ GABRR2 P28476 2/20 0.38
▸ GABRR3 A8MPY1 1/20 0.38
▸ LMNA P02545 1/20 0.38
▸ TSHR P16473 1/20 0.38
▸ APEX1 P27695 1/20 0.38
▸ NPSR1 Q6W5P4 1/20 0.38
▸ TDP1 Q9NUW8 1/20 0.38
▸ CNR1 P21554 1/20 0.37
▸ PPARG P37231 2/20 0.37
▸ PPARA Q07869 2/20 0.37
▸ HIF1A Q16665 2/20 0.36
▸ EPAS1 Q99814 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3814942 1.00 KDM1A (0.42) KDM1APTPN1ALDH1A1MAPTBLM
SCHEMBL15542350 0.98 PTPN1 (0.45) KDM1APTPN1ALDH1A1MAPTBLM
SCHEMBL1740084 0.98 PTPN1 (0.45) KDM1APTPN1ALDH1A1MAPTBLM
SCHEMBL5654022 0.98 PTPN1 (0.45) KDM1APTPN1ALDH1A1MAPTBLM
SCHEMBL23924379 0.98 PTPN1 (0.45) KDM1APTPN1ALDH1A1MAPTBLM
SCHEMBL23924669 0.98 PTPN1 (0.45) KDM1APTPN1ALDH1A1MAPTBLM
SCHEMBL5654028 0.98 PTPN1 (0.45) KDM1APTPN1ALDH1A1MAPTBLM
SCHEMBL5654019 0.98 PTPN1 (0.45) KDM1APTPN1ALDH1A1MAPTBLM
SCHEMBL301125 0.98 PTPN1 (0.45) KDM1APTPN1ALDH1A1MAPTBLM
SCHEMBL22555602 0.98 PTPN1 (0.45) KDM1APTPN1ALDH1A1MAPTBLM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 71 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190010522-A1 METHODS OF MAKING CAPSINOIDS BY BIOSYNTHETIC PROCESSES CONAGEN INC. (US) 2019-01-10 — — US claimed
EP-3377057-A1 METHODS OF MAKING CAPSINOIDS BY BIOSYNTHETIC PROCESSES Conagen Inc. (US) 2018-09-26 — — EP claimed
WO-2017120473-A1 METHODS OF MAKING CAPSINOIDS BY BIOSYNTHETIC PROCESSES CONAGEN INC. (US) 2017-07-13 — — WO claimed
CN-100500142-C Preparation and purification of synthetic capsaicin ALGORX (US) 2009-06-17 — — CN claimed
US-20070293703-A1 Preparation and purification of synthetic capsaicin ALGORX PHARMACEUTICALS, INC. (US) 2007-12-20 — — US claimed
EP-1615880-A4 PREPARATION AND PURIFICATION OF SYNTHETIC TRANS CAPSAICIN ALGORX PHARMACEUTICALS INC (US) 2007-03-07 — — EP claimed
CN-1852707-A Preparation and purification of synthetic capsaicin ALGORX (US) 2006-10-25 — — CN claimed
EP-1615880-A2 PREPARATION AND PURIFICATION OF SYNTHETIC CAPSAICIN Algorx Pharmaceuticals, Inc. (US) 2006-01-18 — — EP claimed
US-20050085652-A1 Preparation and purification of synthetic capsaicin ALGORX PHARMACEUTICALS, INC. (US) 2005-04-21 — — US claimed
WO-2004092122-A2 PREPARATION AND PURIFICATION OF SYNTHETIC CAPSAICIN ALGORX PHARMACEUTICALS, INC. (US) 2004-10-28 — — WO claimed
CN-109790513-B Methods for microbial production of specific natural capsaicin 科纳根公司 2023-04-18 — — CN disclosed
US-20220389433-A1 HIGH YIELD ROUTE FOR THE PRODUCTION OF COMPOUNDS FROM RENEWABLE SOURCES ZYMOCHEM, INC. 2022-12-08 — — US disclosed
US-20200375926-A1 INJECTABLE RESINIFERATOXIN AVENUE VENTURE OPPORTUNITIES FUND, L.P., AS AGENT 2020-12-03 — — US disclosed
US-20200255840-A1 HIGH YIELD ROUTE FOR THE PRODUCTION OF 1, 6-HEXANEDIOL ZYMOCHEM INC (US) 2020-08-13 — — US disclosed
US-10655150-B2 Methods of making capsinoids by biosynthetic processes CONAGEN INC. (US) 2020-05-19 — — US disclosed
US-20040156931-A1 Administration of capsaicinoids ALGORX 2004-08-12 — — US disclosed
WO-2004058286-A1 ADMINISTRATION OF CAPSAICINOIDS ALGORX PHARMACEUTICALS, INC. (US) 2004-07-15 — — WO disclosed
WO-2004056305-A2 ADMINISTRATION OF CAPSAICINOIDS ALGORX (US) 2004-07-08 — — WO disclosed
US-6333421-B1 SUBSTANCES HAVING IMMUNOPOTENTIATING AND ENERGY METABOLISM ENHANCING ACTIVITY MORINAGA & CO., LTD. (JP) 2001-12-25 — — US disclosed
EP-1069105-A1 NOVEL CAPSAICINOIDE-LIKE SUBSTANCES HAVING ESTER BOND MORINAGA & CO., LTD. (JP) 2001-01-17 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050085652-A1 Preparation and purification of synthetic capsaicin TRPV1, TRPV5, TAC3 KDM1A 4081/4885PTPN1 2961/4885ALDH1A1 2674/4885
US-20190010522-A1 METHODS OF MAKING CAPSINOIDS BY BIOSYNTHETIC PROCESSES FADS2, COASY, FASN KDM1A 2351/4885PTPN1 4320/4885ALDH1A1 828/4885
US-20070293703-A1 Preparation and purification of synthetic capsaicin TRPV1, TRPV5, TAC3 KDM1A 4081/4885PTPN1 2961/4885ALDH1A1 2674/4885
US-10655150-B2 Methods of making capsinoids by biosynthetic processes FADS2, COASY, FASN KDM1A 2351/4885PTPN1 4320/4885ALDH1A1 828/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.