Alcohol

Alcohol

SCHEMBL8073598

CCCCCCCCCC1(Oc2ccccc2)CO1.CCO

nearest known ligand 0.41

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MMP8 known ✓ P22894 2/20 0.41
MMP13 known ✓ P45452 2/20 0.41
MMP2 P08253 4/20 0.41
MMP9 P14780 4/20 0.41
MMP3 P08254 2/20 0.41
OPRK1 P41145 2/20 0.37
ZDHHC2 Q9UIJ5 1/20 0.37
OPRM1 P35372 1/20 0.37
OPRD1 P41143 1/20 0.37
OPRL1 P41146 1/20 0.37
LTA4H P09960 2/20 0.37
MLNR O43193 1/20 0.36
NR1I2 O75469 1/20 0.36
ESR1 P03372 1/20 0.36
NR3C1 P04150 1/20 0.36
PGR P06401 1/20 0.36
ADRB2 P07550 1/20 0.36
CHRM2 P08172 1/20 0.36
ADRB1 P08588 1/20 0.36
HTR1A P08908 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methyl Alcohol SCHEMBL11123438 0.95 MMP2 (0.42) MMP2MMP9MMP3MMP8MMP13
SCHEMBL7721179 0.95 MMP2 (0.44) MMP2MMP9MMP3MMP8MMP13
SCHEMBL5416450 0.95 MMP2 (0.44) MMP2MMP9MMP3MMP8MMP13
SCHEMBL11499462 0.95 MMP2 (0.44) MMP2MMP9MMP3MMP8MMP13
SCHEMBL1878427 0.84 MMP2 (0.42) MMP2MMP9MMP3MMP8MMP13
SCHEMBL287632 0.84 MMP2 (0.42) MMP2MMP9MMP3MMP8MMP13
SCHEMBL289725 0.84 MMP2 (0.42) MMP2MMP9MMP3MMP8MMP13
SCHEMBL498620 0.84 MMP2 (0.42) MMP2MMP9MMP3MMP8MMP13
SCHEMBL11592255 0.80 MMP2 (0.40) MMP2MMP9MMP3MMP8MMP13
SCHEMBL8041834 0.80 MMP2 (0.40) MMP2MMP9MMP3MMP8MMP13

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4777112-A THE POLYETHER HYDROGEN-BONDED TO ANOTHER POLYMER AND SALT OF POLYVINYLHYDROGEN PHTHALATE POLAROID CORPORATION (US) 1988-10-11 US claimed
EP-0027461-A4 COLOR TRANSFER FILM AND PROCESS. POLAROID CORP (US) 1982-07-12 EP claimed
US-4298674-A WHEREIN PROCESSING COMPOSITION INCLUDES LIGHT-REFLECTING PIGMENT AND PH-SENSITIVE OPTICAL FILTER POLAROID CORPORATION (US) 1981-11-03 US claimed
EP-0027461-A1 COLOR TRANSFER FILM AND PROCESS. POLAROID CORP (US) 1981-04-29 EP claimed
WO-1980002333-A1 COLOR TRANSFER FILM AND PROCESS POLAROID CORP (US) 1980-10-30 WO claimed
US-6103912-A OPTICAL INFRARED FILTERS COMPRISING PH SENSITIVE DYES POLAROID CORPORATION (US) 2000-08-15 US disclosed
EP-0823068-B1 COLOR-PROVIDING COMPOUNDS POLAROID CORP (US) 2000-08-09 EP disclosed
EP-0683430-B1 Photographic processing compositions including hydrophobically modified thickening agent POLAROID CORP (US) 1999-03-31 EP disclosed
EP-0553346-B1 PHOTOGRAPHIC PRODUCTS AND PROCESSES POLAROID CORP (US) 1998-01-28 EP disclosed
US-5658705-A HEAT DEVELOPABLE POLAROID CORPORATION (US) 1997-08-19 US disclosed
EP-0683430-A2 Photographic processing compositions including hydrophobically modified thickening agent POLAROID CORPORATION (US) 1995-11-22 EP disclosed
US-5422233-A Based on a copolymer of an acrylic acid and an acrylic ester or amide in an aqueous alkali solution of pH 10+; self-development/photo/; diffusion transfer; nonpooling; nonhydrolyzing; nonseparating POLAROID CORPORATION (US) 1995-06-06 US disclosed
US-4503138-A DIFFUSION TRANSFER POLAROID CORPORATION (US) 1985-03-05 US disclosed
EP-0027461-A4 COLOR TRANSFER FILM AND PROCESS. POLAROID CORP (US) 1982-07-12 EP disclosed
US-4298674-A WHEREIN PROCESSING COMPOSITION INCLUDES LIGHT-REFLECTING PIGMENT AND PH-SENSITIVE OPTICAL FILTER POLAROID CORPORATION (US) 1981-11-03 US disclosed
US-4294907-A DIFFUSION TRANSFER FILMS POLAROID CORPORATION (US) 1981-10-13 US disclosed
EP-0027461-A1 COLOR TRANSFER FILM AND PROCESS. POLAROID CORP (US) 1981-04-29 EP disclosed
US-4264507-A Novel xanthene dye developers POLAROID CORPORATION (US) 1981-04-28 US disclosed
US-4264704-A Novel xanthene dye developers POLAROID CORPORATION (US) 1981-04-28 US disclosed
WO-1980002333-A1 COLOR TRANSFER FILM AND PROCESS POLAROID CORP (US) 1980-10-30 WO disclosed