SCHEMBL8073695

SCHEMBL8073695

CC(C)(C)N[Si](C)(C)C1C=C(c2ccccc2)c2cc3c(cc21)CCC3.[LiH].[LiH]

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6151121 0.99
SCHEMBL7036545 0.79 KDM4E (0.35)
SCHEMBL7047350 0.67
SCHEMBL6296910 0.66 MEN1 (0.32)
SCHEMBL7949383 0.66
SCHEMBL4638183 0.65
SCHEMBL7632634 0.63
SCHEMBL20814983 0.62
SCHEMBL22607499 0.62
SCHEMBL25270117 0.62 NPC1 (0.37)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1040161-A1 SEALS PRODUCED FROM ALPHA-OLEFIN/VINYLIDENE AROMATIC AND/OR HINDERED ALIPHATIC VINYLIDENE/INTERPOLYMER BASED MATERIALS AND SEALING SYSTEMS THEREFROM THE DOW CHEMICAL COMPANY (US) 2000-10-04 EP disclosed
WO-1999031176-A1 SEALS PRODUCED FROM ALPHA-OLEFIN/VINYLIDENE AROMATIC AND/OR HINDERED ALIPHATIC VINYLIDENE/INTERPOLYMER BASED MATERIALS AND SEALING SYSTEMS THEREFROM THE DOW CHEMICAL COMPANY (US) 1999-06-24 WO disclosed