SCHEMBL7632634

SCHEMBL7632634

CC1=CC([Si](C)(C)NC(C)(C)C)c2ccccc21

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6907559 0.80 GPR3 (0.33)
SCHEMBL6907806 0.80 GAA (0.31)
SCHEMBL6911227 0.79 LMNA (0.35)
Hydrochloric Acid SCHEMBL7186892 0.78 GPR3 (0.31)
Hydrochloric Acid SCHEMBL6861887 0.78 GPR3 (0.31)
Hydrochloric Acid SCHEMBL6858902 0.78 GAA (0.30)
Hydrochloric Acid SCHEMBL6851880 0.78 GAA (0.30)
Hydrochloric Acid SCHEMBL6851892 0.78 GAA (0.30)
Hydrochloric Acid SCHEMBL6861885 0.78 GPR3 (0.31)
Hydrochloric Acid SCHEMBL7186886 0.78 GPR3 (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0874860-B1 SUBSTITUTED INDENYL CONTAINING METAL COMPLEXES AND OLEFIN POLYMERIZATION PROCESS DOW CHEMICAL CO (US) 2002-11-13 EP disclosed
US-6015868-A CATALYSIS OF HIGH TEMPERATURE, SOLUTION POLYMERIZATION WHICH YIELDS HIGH MOLECULAR WEIGHT OLEFIN POLYMERS, BY USING COORDINATION CATALYST MIXED WITH AN ACTIVATING COCATALYST, EFFICIENCY THE DOW CHEMICAL COMPANY (US) 2000-01-18 US disclosed