SCHEMBL6296910

SCHEMBL6296910

CC(C)(C)N[Si](C)(C)C1C=C(c2ccccc2)C(c2ccccc2)=C1

nearest known ligand 0.32

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
IDH2 P48735 1/20 0.31
IDO1 P14902 1/20 0.31
BACE1 P56817 1/20 0.31
MAPT P10636 1/20 0.30
ATM Q13315 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22607499 0.94
SCHEMBL7510367 0.63 GPR3 (0.36) MEN1KMT2AATM
SCHEMBL6273804 0.62 ESR1 (0.37) MEN1KMT2AATM
SCHEMBL7632190 0.62 HRH1 (0.40) MAPTATM
Hydrochloric Acid SCHEMBL6862745 0.61 GPR3 (0.34) MEN1KMT2AATM
Hydrochloric Acid SCHEMBL7645556 0.59 SLC6A3 (0.38) MEN1KMT2AMAPTATM
SCHEMBL11540362 0.59 ATM (0.38) IDH2ATM
SCHEMBL6902982 0.59 ESR1 (0.39) MAPTATM
SCHEMBL686819 0.58 ATM (0.36) IDH2ATM
Biphenyl SCHEMBL27745920 0.58 ALDH1A1 (0.69) MAPTATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6946531-B2 Low molecular weight ethylene interpolymers and polymerization process DOW GLOBAL TECHNOLOGIES INC. (US) 2005-09-20 US disclosed
EP-1389215-B1 3-ARYL-SUBSTITUTED CYCLOPENTADIENYL METAL COMPLEXES AND POLYMERIZATION PROCESS DOW GLOBAL TECHNOLOGIES INC (US) 2005-06-15 EP disclosed
US-6825147-B2 (3,4-DIPHENYLCYCLOPENTADIEN-1-YL)DIMETHYL(T-BUTYLAMIDO) -SILANETITANIUM DICHLORIDE, FOR EXAMPLE; FOR COPOLYMERIZATION OF ETHYLENE AND STYRENE DOW GLOBAL TECHNOLOGIES INC. 2004-11-30 US disclosed
US-20040092680-A1 Addition copolymerization using titanium complexes comprising a 3-aryl-substituted cyclopentadienyl ring as polymerization catalyst DOW GLOBAL TECHNOLOGIES LLC 2004-05-13 US disclosed
EP-1389215-A1 3-ARYL-SUBSTITUTED CYCLOPENTADIENYL METAL COMPLEXES AND POLYMERIZATION PROCESS DOW GLOBAL TECHNOLOGIES INC. (US) 2004-02-18 EP disclosed
US-20020183464-A1 3-aryl-substituted cyclopentadienyl metal complexes and polymerization process DOW GLOBAL TECHNOLOGIES LLC 2002-12-05 US disclosed
WO-2002092610-A1 3-ARYL-SUBSTITUTED CYCLOPENTADIENYL METAL COMPLEXES AND POLYMERIZATION PROCESS DOW GLOBAL TECHNOLOGIES INC. (US) 2002-11-21 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020183464-A1 3-aryl-substituted cyclopentadienyl metal complexes and polymerization process SOD1, AOC3, PPOX MEN1 4838/4885KMT2A 2742/4885IDH2 2359/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.