SCHEMBL8073864 — predicted protein targets

Predicted protein targets (top 9)

	gene	UniProt	supporting neighbours	confidence
▸	DPP4	P27487	13/20	0.41

▸	DPP7	Q9UHL4	7/20	0.40

▸	KCNH2	Q12809	3/20	0.39

▸	DPP8	Q6V1X1	6/20	0.38

▸	DPP9	Q86TI2	6/20	0.38

▸	HRH2	P25021	3/20	0.38

▸	HRH1	P35367	3/20	0.38

▸	HRH3	Q9Y5N1	3/20	0.37

▸	ACACB	O00763	1/20	0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL2891614	0.83	GPR119 (0.40)	DPP4DPP7KCNH2DPP8DPP9
SCHEMBL2891620	0.83	GPR119 (0.40)	DPP4DPP7KCNH2DPP8DPP9
SCHEMBL8065616	0.83	HRH2 (0.41)	DPP4DPP7KCNH2HRH2HRH1
SCHEMBL2900045	0.81	GPR119 (0.42)	DPP4DPP7KCNH2DPP8DPP9
SCHEMBL2900039	0.81	GPR119 (0.42)	DPP4DPP7KCNH2DPP8DPP9
SCHEMBL8079590	0.76	DPP4 (0.39)	DPP4DPP7
SCHEMBL2900068	0.75	GPR119 (0.44)	DPP4DPP7KCNH2HRH2HRH1
SCHEMBL2900069	0.75	GPR119 (0.44)	DPP4DPP7KCNH2HRH2HRH1
SCHEMBL8076548	0.74	HRH2 (0.38)	DPP4DPP7KCNH2HRH2HRH1
SCHEMBL2900440	0.70	GPR119 (0.47)	DPP4DPP7KCNH2HRH3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2009034388-A1	COMPOUNDS FOR THE TREATMENT OF METABOLIC DISORDERS	PROSIDION LIMITED (GB)	2009-03-19	—	—	WO	disclosed