Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH2 | P25021 | 12/20 | 0.38 |
| ▸ | HRH1 | P35367 | 12/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.35 |
| ▸ | DPP4 | P27487 | 3/20 | 0.33 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2897679 | 0.85 | GPR119 (0.42) | HRH2HRH1GPR119KCNH2 | |
| SCHEMBL2897674 | 0.85 | GPR119 (0.42) | HRH2HRH1GPR119KCNH2 | |
| SCHEMBL2897676 | 0.85 | GPR119 (0.42) | HRH2HRH1GPR119KCNH2 | |
| SCHEMBL8065616 | 0.83 | HRH2 (0.41) | HRH2HRH1GPR119DPP4DPP7 | |
| SCHEMBL3696786 | 0.82 | GPR119 (0.50) | GPR119 | |
| SCHEMBL2891416 | 0.82 | GPR119 (0.50) | GPR119 | |
| SCHEMBL10101202 | 0.80 | HRH2 (0.36) | HRH2HRH1DPP4DPP7KCNH2 | |
| SCHEMBL8066212 | 0.80 | PTPN1 (0.37) | HRH2HRH1GPR119 | |
| SCHEMBL8057985 | 0.79 | HRH2 (0.35) | HRH2HRH1GPR119 | |
| SCHEMBL865096 | 0.78 | TRPA1 (0.37) | HRH2HRH1DPP4DPP7KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009034388-A1 | COMPOUNDS FOR THE TREATMENT OF METABOLIC DISORDERS | PROSIDION LIMITED (GB) | 2009-03-19 | — | — | WO | disclosed |