SCHEMBL8074009

SCHEMBL8074009

CO[Si](OC)(N1CCCC(C)C1)C(C)(C)C

nearest known ligand 0.32

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.31
LMNA P02545 1/20 0.31
POLB P06746 1/20 0.31
RECQL P46063 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7615563 0.77
SCHEMBL8073748 0.76
SCHEMBL8059599 0.74
SCHEMBL9853283 0.74 ALDH1A1 (0.36) ALDH1A1LMNAPOLBRECQL
SCHEMBL14460044 0.74
SCHEMBL10248897 0.66 ALDH1A1 (0.37) ALDH1A1LMNAPOLBRECQLSMN1; SMN2
SCHEMBL681120 0.66 ALDH1A1 (0.37) ALDH1A1LMNAPOLBRECQLSMN1; SMN2
SCHEMBL793443 0.66 ALDH1A1 (0.37) ALDH1A1LMNAPOLBRECQLSMN1; SMN2
SCHEMBL7777135 0.66 ACHE (0.30)
SCHEMBL7609332 0.66 ALDH1A1 (0.30) ALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6165930-A Organosilane compounds MONTELL NORTH AMERICA INC. (US) 2000-12-26 US disclosed
EP-0410443-B1 Organosilane compounds HIMONT INC (US) 1995-01-11 EP disclosed
US-5166340-A Polymerization catalysts, coordination catalysts for olefin polymerization HIMONT INCORPORATED (US) 1992-11-24 US disclosed
EP-0410443-A1 Organosilane compounds MONTELL NORTH AMERICA INC. (US) 1991-01-30 EP disclosed