Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 2/20 | 0.39 |
| ▸ | AGXT | P21549 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | APP | P05067 | 7/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | GBA1 | P04062 | 1/20 | 0.35 |
| ▸ | UGCG | Q16739 | 1/20 | 0.35 |
| ▸ | GBA2 | Q9HCG7 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8074066 | 1.00 | TDP1 (0.42) | TDP1L3MBTL1IDO1AGXTNPC1 | |
| SCHEMBL12769262 | 0.83 | GLA (0.39) | TDP1L3MBTL1IDO1AGXTNPC1 | |
| SCHEMBL12769950 | 0.83 | GLA (0.39) | TDP1L3MBTL1IDO1AGXTNPC1 | |
| SCHEMBL8076909 | 0.80 | PDE4D (0.47) | TDP1L3MBTL1IDO1AGXTNPC1 | |
| SCHEMBL8076913 | 0.80 | PDE4D (0.47) | TDP1L3MBTL1IDO1AGXTNPC1 | |
| SCHEMBL22601882 | 0.78 | L3MBTL1 (0.55) | TDP1L3MBTL1IDO1AGXTHTT | |
| SCHEMBL8076927 | 0.77 | TDP1 (0.43) | TDP1L3MBTL1IDO1AGXTCA1 | |
| SCHEMBL12769971 | 0.76 | GLA (0.39) | TDP1L3MBTL1IDO1AGXTNPC1 | |
| SCHEMBL24114691 | 0.74 | L3MBTL1 (0.50) | TDP1L3MBTL1 | |
| SCHEMBL12769967 | 0.73 | TDP1 (0.40) | TDP1L3MBTL1IDO1AGXTCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1026155-A1 | VITAMIN D DERIVATIVES AND PROCESS FOR PRODUCING THE SAME | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2000-08-09 | — | — | EP | disclosed |