Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.65 |
| ▸ | TP53 | P04637 | 3/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA4 | P22748 | 1/20 | 0.50 |
| ▸ | CA6 | P23280 | 1/20 | 0.50 |
| ▸ | CA5A | P35218 | 1/20 | 0.50 |
| ▸ | CA7 | P43166 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.50 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | PPARG | P37231 | 1/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.48 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.48 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8074114 | 0.97 | LMNA (0.67) | LMNATP53CA12CA1CA2 | |
| SCHEMBL27885 | 0.80 | LMNA (1.00) | LMNATP53CA12CA1CA2 | |
| SCHEMBL4964940 | 0.77 | LMNA (0.62) | LMNATP53CA12CA1CA2 | |
| SCHEMBL23486695 | 0.75 | LMNA (0.88) | LMNATP53CA12CA1CA2 | |
| SCHEMBL23141119 | 0.74 | LMNA (0.86) | LMNATP53CA12CA1CA2 | |
| SCHEMBL29403429 | 0.73 | LMNA (0.84) | LMNATP53CA12CA1CA2 | |
| SCHEMBL16265376 | 0.73 | LMNA (0.66) | LMNATP53PSMB8RAB9APPARG | |
| SCHEMBL1928662 | 0.73 | CA12 (0.85) | LMNATP53CA12CA1CA2 | |
| SCHEMBL6243996 | 0.73 | CA12 (0.85) | LMNATP53CA12CA1CA2 | |
| SCHEMBL1614489 | 0.73 | LMNA (0.83) | LMNATP53CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6103761-A | Agents acting at cholecystokinin receptors | WARNER-LAMBERT COMPANY (US) | 2000-08-15 | — | — | US | disclosed |