SCHEMBL8074121

SCHEMBL8074121

O=C(Oc1ccc(C(F)(F)F)cc1)c1ccc(O)cc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PRSS1 P07477 2/20 0.64
ACR P10323 2/20 0.64
KIF11 P52732 2/20 0.51
CES2 O00748 1/20 0.50
CES1 P23141 1/20 0.50
MAPT P10636 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
HSD17B10 Q99714 1/20 0.50
P4HB P07237 1/20 0.50
CYP1A1 P04798 1/20 0.50
CYP1B1 Q16678 1/20 0.50
TRPV1 Q8NER1 1/20 0.49
MAOB P27338 2/20 0.48
ELANE P08246 1/20 0.47
LMNA P02545 1/20 0.47
CYP11B1 P15538 1/20 0.46
CYP11B2 P19099 1/20 0.46
NQO2 P16083 1/20 0.45
PTGS1 P23219 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14640734 1.00 PRSS1 (0.64) PRSS1ACRKIF11CES2CES1
SCHEMBL14640390 1.00 PRSS1 (0.64) PRSS1ACRKIF11CES2CES1
SCHEMBL14679456 0.95 KIF11 (0.59) PRSS1ACRKIF11CES2CES1
SCHEMBL9682438 0.93 PRSS1 (0.71) PRSS1ACRKIF11CES2CES1
SCHEMBL28639038 0.93 PRSS1 (0.71) PRSS1ACRKIF11CES2CES1
SCHEMBL28641893 0.86 PRSS1 (0.64) PRSS1ACRKIF11CES2CES1
SCHEMBL9696072 0.85 HSD17B10 (0.59) PRSS1MAPTHSD17B10ELANELMNA
SCHEMBL16493489 0.85 HSD17B10 (0.59) PRSS1MAPTHSD17B10ELANELMNA
SCHEMBL740606 0.85 HSD17B10 (0.59) PRSS1MAPTHSD17B10ELANELMNA
SCHEMBL688276 0.85 HSD17B10 (0.59) PRSS1MAPTHSD17B10ELANELMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10175573-B2 Curable composition and color filter FUJIFILM CORPORATION (JP) 2019-01-08 US disclosed
US-20150316844-A1 CURABLE COMPOSITION AND COLOR FILTER FUJIFILM CORPORATION (JP) 2015-11-05 US disclosed
US-20150316844-A1 CURABLE COMPOSITION AND COLOR FILTER FUJIFILM CORPORATION (JP) 2015-11-05 US disclosed
US-6013748-A RADIATION TRANSPARENT OPTICAL FILM JAPAN AS REPRESENTED BY DIRECTOR GENERAL OF AGENCY OF INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) 2000-01-11 US disclosed