Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
| ▸ | CA9 | Q16790 | 2/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA7 | P43166 | 1/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | CFTR | P13569 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | CA5A | P35218 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28347585 | 0.90 | CA12 (0.46) | CA1CA2CA9CA12CA7 | |
| SCHEMBL28023544 | 0.90 | TSHR (0.43) | CA1CA2CA9CA12CA7 | |
| SCHEMBL9715761 | 0.86 | TSHR (0.44) | CA1CA2CA9CA12CA7 | |
| SCHEMBL26617428 | 0.84 | CA1 (0.50) | CA1CA2CA9CA12CA7 | |
| SCHEMBL61520 | 0.84 | TSHR (0.55) | CA1CA2CA9LMNATSHR | |
| SCHEMBL5047779 | 0.83 | LMNA (0.46) | CA1CA2CA9CA12CA7 | |
| SCHEMBL30280797 | 0.83 | ALDH1A1 (0.48) | CA1CA2CA9CA12CA7 | |
| SCHEMBL16958924 | 0.83 | ALDH1A1 (0.48) | CA1CA2CA9CA12CA7 | |
| SCHEMBL5198420 | 0.83 | KDM4E (0.57) | CA1CA2CA9CA12CA7 | |
| SCHEMBL13954078 | 0.83 | CA1 (0.69) | CA1CA2CA9CA12CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3720597-B1 | MACROMOLECULAR COMPOSITIONS COMPRISING INDENE-DERIVATIVES | STICHTING TECHNISCHE WETENSCHAPPEN (NL) | 2023-11-29 | — | — | EP | claimed |
| US-11612877-B2 | Macromolecular compositions comprising indene-derivatives, preparation thereof, and use thereof | STICHTING VOOR DE TECHNISCHE WETENSCHAPPEN (NL) | 2023-03-28 | — | — | US | claimed |
| US-20200368721-A1 | Macromolecular compositions comprising indene-derivatives, preparation thereof, and use thereof | STICHTING VOOR DE TECHNISCHE WETENSCHAPPEN (NL) | 2020-11-26 | — | — | US | claimed |
| EP-3720597-A1 | MACROMOLECULAR COMPOSITIONS COMPRISING INDENE-DERIVATIVES, PREPARATION THEREOF, AND USE THEREOF | Stichting voor de Technische Wetenschappen (NL) | 2020-10-14 | — | — | EP | claimed |
| WO-2019110557-A1 | MACROMOLECULAR COMPOSITIONS COMPRISING INDENE-DERIVATIVES, PREPARATION THEREOF, AND USE THEREOF | STICHTING VOOR DE TECHNISCHE WETENSCHAPPEN (NL) | 2019-06-13 | — | — | WO | claimed |
| US-12318756-B2 | Macromolecular compositions comprising indene-derivatives, preparation thereof, and use thereof | UNIVERSITEIT UTRECHT HOLDING B.V. (NL) | 2025-06-03 | — | — | US | disclosed |
| EP-3720597-B1 | MACROMOLECULAR COMPOSITIONS COMPRISING INDENE-DERIVATIVES | STICHTING TECHNISCHE WETENSCHAPPEN (NL) | 2023-11-29 | — | — | EP | disclosed |
| EP-3720597-B1 | MACROMOLECULAR COMPOSITIONS COMPRISING INDENE-DERIVATIVES | STICHTING TECHNISCHE WETENSCHAPPEN (NL) | 2023-11-29 | — | — | EP | disclosed |
| US-20230201799-A1 | Macromolecular compositions comprising indene-derivatives, preparation thereof, and use thereof | STICHTING VOOR DE TECHNISCHE WETENSCHAPPEN (NL) | 2023-06-29 | — | — | US | disclosed |
| US-20230201799-A1 | Macromolecular compositions comprising indene-derivatives, preparation thereof, and use thereof | STICHTING VOOR DE TECHNISCHE WETENSCHAPPEN (NL) | 2023-06-29 | — | — | US | disclosed |
| US-20230201799-A1 | Macromolecular compositions comprising indene-derivatives, preparation thereof, and use thereof | STICHTING VOOR DE TECHNISCHE WETENSCHAPPEN (NL) | 2023-06-29 | — | — | US | disclosed |
| US-11612877-B2 | Macromolecular compositions comprising indene-derivatives, preparation thereof, and use thereof | STICHTING VOOR DE TECHNISCHE WETENSCHAPPEN (NL) | 2023-03-28 | — | — | US | disclosed |
| US-20200368721-A1 | Macromolecular compositions comprising indene-derivatives, preparation thereof, and use thereof | STICHTING VOOR DE TECHNISCHE WETENSCHAPPEN (NL) | 2020-11-26 | — | — | US | disclosed |
| US-20200368721-A1 | Macromolecular compositions comprising indene-derivatives, preparation thereof, and use thereof | STICHTING VOOR DE TECHNISCHE WETENSCHAPPEN (NL) | 2020-11-26 | — | — | US | disclosed |
| EP-3720597-A1 | MACROMOLECULAR COMPOSITIONS COMPRISING INDENE-DERIVATIVES, PREPARATION THEREOF, AND USE THEREOF | Stichting voor de Technische Wetenschappen (NL) | 2020-10-14 | — | — | EP | disclosed |
| WO-2019110557-A1 | MACROMOLECULAR COMPOSITIONS COMPRISING INDENE-DERIVATIVES, PREPARATION THEREOF, AND USE THEREOF | STICHTING VOOR DE TECHNISCHE WETENSCHAPPEN (NL) | 2019-06-13 | — | — | WO | disclosed |
| WO-2019110557-A1 | MACROMOLECULAR COMPOSITIONS COMPRISING INDENE-DERIVATIVES, PREPARATION THEREOF, AND USE THEREOF | STICHTING VOOR DE TECHNISCHE WETENSCHAPPEN (NL) | 2019-06-13 | — | — | WO | disclosed |
| EP-1012201-A1 | POLY(ARYL VINYLENE)S | White Knight Technologies Limited (GB) | 2000-06-28 | — | — | EP | disclosed |
| WO-1999014255-A1 | POLY(ARYL VINYLENE)S | WHITE KNIGHT TECHNOLOGIES LIMITED (GB) | 1999-03-25 | — | — | WO | disclosed |