Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10154383 | 0.82 | RIPK1 (0.31) | — | |
| SCHEMBL4971072 | 0.82 | SMN1; SMN2 (0.33) | SMN1; SMN2 | |
| SCHEMBL807417 | 0.81 | SMN1; SMN2 (0.30) | SMN1; SMN2 | |
| SCHEMBL10142225 | 0.80 | SMN1; SMN2 (0.30) | SMN1; SMN2 | |
| SCHEMBL4974309 | 0.79 | SMN1; SMN2 (0.32) | SMN1; SMN2 | |
| SCHEMBL10142092 | 0.79 | SMN1; SMN2 (0.32) | SMN1; SMN2 | |
| SCHEMBL10154121 | 0.78 | TMPRSS2 (0.31) | — | |
| SCHEMBL4967938 | 0.78 | POLRMT (0.48) | — | |
| SCHEMBL10142123 | 0.78 | — | — | |
| SCHEMBL807412 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012037038-A1 | 2' -FLUORO SUBSTITUTED CARBA-NUCLEOSIDE ANALOGS FOR ANTIVIRAL TREATMENT | GILEAD SCIENCES, INC. (US) | 2012-03-22 | — | — | WO | disclosed |