Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LARS1 | Q9P2J5 | 3/20 | 0.44 |
| ▸ | AGTR1 | P30556 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | ANPEP | P15144 | 1/20 | 0.40 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.40 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ELANE | P08246 | 1/20 | 0.40 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MMP8 | P22894 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6761546 | 0.87 | KDM4E (0.45) | AGTR1KDM4ERAB9AALDH1A1HSD17B10 | |
| SCHEMBL6303080 | 0.86 | AGTR1 (0.44) | AGTR1KDM4ERAB9AALDH1A1HSD17B10 | |
| SCHEMBL9716704 | 0.82 | KDM4E (0.49) | AGTR1KDM4ERAB9AALDH1A1HSD17B10 | |
| SCHEMBL8166016 | 0.81 | MME (0.41) | AGTR1KDM4ERAB9AALDH1A1HSD17B10 | |
| SCHEMBL11819594 | 0.80 | KDM4E (0.46) | AGTR1KDM4ERAB9AALDH1A1HSD17B10 | |
| SCHEMBL11800788 | 0.80 | KDM4E (0.46) | AGTR1KDM4ERAB9AALDH1A1HSD17B10 | |
| SCHEMBL5967407 | 0.77 | KDM4E (0.50) | AGTR1KDM4ERAB9AALDH1A1HSD17B10 | |
| Leucine SCHEMBL11019375 | 0.75 | SLC7A5 (0.55) | LARS1ALDH1A1HSD17B10ANPEPRNPEP | |
| Leucine SCHEMBL11019376 | 0.75 | SLC7A5 (0.55) | LARS1ALDH1A1HSD17B10ANPEPRNPEP | |
| Methylamine SCHEMBL5383831 | 0.74 | AGTR1 (0.50) | AGTR1KDM4ERAB9AALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1038533-A1 | MEDICINAL COMPOSITIONS FOR TREATING IMMUNODEFICIENCY DISEASES | Nippon Kayaku Kabushiki Kaisha (JP) | 2000-09-27 | — | — | EP | disclosed |
| EP-0347820-B1 | NOVEL SPERGUALIN-RELATED COMPOUNDS AND PREPARATION AND APPLICATION OF THE SAME | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1993-04-21 | — | — | EP | disclosed |
| US-5061787-A | IMMUNOSUPPRESSANTS | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1991-10-29 | — | — | US | disclosed |
| EP-0241797-B1 | NOVEL SPERGUALIN-RELATED COMPOUNDS AND PROCESS FOR PRODUCING THE SAME | MICROBIAL CHEMISTRY RESEARCH FOUNDATION (JP) | 1991-06-12 | — | — | EP | disclosed |
| US-4956504-A | IMMUNOMODULATORS, ANTIBIOTICS | ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) | 1990-09-11 | — | — | US | disclosed |
| EP-0347820-A1 | Novel spergualin-related compounds and preparation and application of the same | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1989-12-27 | — | — | EP | disclosed |
| EP-0241797-A2 | Novel spergualin-related compounds and process for producing the same | MICROBIAL CHEMISTRY RESEARCH FOUNDATION (JP) | 1987-10-21 | — | — | EP | disclosed |