Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | AGTR1 | P30556 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.41 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.41 |
| ▸ | ITGAV | P06756 | 1/20 | 0.41 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.40 |
| ▸ | CDC25A | P30304 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11800788 | 0.87 | KDM4E (0.46) | KDM4EAGTR1RAB9AALDH1A1HSD17B10 | |
| SCHEMBL11819594 | 0.87 | KDM4E (0.46) | KDM4EAGTR1RAB9AALDH1A1HSD17B10 | |
| SCHEMBL8074247 | 0.82 | LARS1 (0.44) | KDM4EAGTR1RAB9AALDH1A1HSD17B10 | |
| SCHEMBL12798712 | 0.82 | L3MBTL1 (0.56) | KDM4EALDH1A1HSD17B10HPGDKMT2A | |
| SCHEMBL6303080 | 0.81 | AGTR1 (0.44) | KDM4EAGTR1RAB9AALDH1A1HSD17B10 | |
| SCHEMBL690246 | 0.81 | KDM4E (0.53) | KDM4EAGTR1RAB9AALDH1A1HSD17B10 | |
| SCHEMBL5967407 | 0.81 | KDM4E (0.50) | KDM4EAGTR1RAB9AALDH1A1HSD17B10 | |
| SCHEMBL341645 | 0.80 | KDM4E (0.71) | KDM4EAGTR1RAB9AALDH1A1HSD17B10 | |
| SCHEMBL29620333 | 0.80 | KDM4E (0.71) | KDM4EAGTR1RAB9AALDH1A1HSD17B10 | |
| SCHEMBL11804263 | 0.80 | AGTR1 (0.47) | KDM4EAGTR1RAB9AALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0178911-B1 | COMPOSITION CONTAINING A PENEM OR CARBAPENEM ANTIBIOTIC | SANKYO COMPANY LIMITED (JP) | 1992-01-22 | — | — | EP | disclosed |
| US-4757066-A | Reduces renal toxicity | SANKYO COMPANY LIMITED (JP) | 1988-07-12 | — | — | US | disclosed |
| EP-0178911-A2 | Composition containing a penem or carbapenem antibiotic | SANKYO COMPANY LIMITED (JP) | 1986-04-23 | — | — | EP | disclosed |