Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC12A2 | P55011 | 1/20 | 0.34 |
| ▸ | SLC12A5 | Q9H2X9 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 3/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | ENPP3 | O14638 | 2/20 | 0.31 |
| ▸ | ENPP1 | P22413 | 2/20 | 0.31 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | DRD1 | P21728 | 1/20 | 0.31 |
| ▸ | DRD4 | P21917 | 1/20 | 0.31 |
| ▸ | DRD5 | P21918 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8074534 | 0.94 | SLC12A2 (0.33) | SLC12A2SLC12A5TP53TSHRHTT | |
| SCHEMBL26837241 | 0.89 | SLC12A2 (0.36) | SLC12A2SLC12A5TP53TSHRHTT | |
| SCHEMBL21565962 | 0.89 | SLC12A2 (0.37) | SLC12A2SLC12A5TP53TSHRHTT | |
| SCHEMBL18729643 | 0.88 | SLC12A2 (0.39) | SLC12A2SLC12A5TP53TSHRHTT | |
| SCHEMBL9424842 | 0.87 | PLA2G2C (0.37) | SLC12A2SLC12A5CYP1A2CYP2D6DRD2 | |
| SCHEMBL9424685 | 0.87 | PLA2G2C (0.37) | SLC12A2SLC12A5CYP1A2CYP2D6DRD2 | |
| SCHEMBL9424847 | 0.87 | PLA2G2C (0.37) | SLC12A2SLC12A5CYP1A2CYP2D6DRD2 | |
| SCHEMBL23766547 | 0.85 | SLC12A2 (0.36) | SLC12A2SLC12A5TP53TSHRHTT | |
| SCHEMBL23766558 | 0.84 | SLC12A2 (0.35) | SLC12A2SLC12A5TP53TSHRHTT | |
| SCHEMBL23766543 | 0.84 | SLC12A2 (0.35) | SLC12A2SLC12A5TP53TSHRHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6093345-A | PYRIMIDINE COMPOUNDS, ELECTROOPTICS | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2000-07-25 | — | — | US | disclosed |
| US-5454976-A | Optical active mixture comprising a fluoro-alkyl phenyl pyrimidine compounds; high contrast ratio, fast response time; optical switches, printer shutter arrays | TAKASAGO INTERNATIONAL CORPORATION (JP) | 1995-10-03 | — | — | US | disclosed |