Dichlorodifluoromethane

Dichlorodifluoromethane

SCHEMBL8075401

FC(F)(Cl)Cl.OCOc1ccccc1

nearest known ligand 0.50

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Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.50
RECQL P46063 1/20 0.50
KCNA3 P22001 1/20 0.44
ALOX15 P16050 1/20 0.43
HDAC1 Q13547 2/20 0.43
HDAC2 Q92769 2/20 0.43
LMNA P02545 1/20 0.41
CYP2C9 P11712 1/20 0.41
CYP2C19 P33261 1/20 0.41
TAAR1 Q96RJ0 1/20 0.40
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
MAOB P27338 3/20 0.39
AOC2 O75106 2/20 0.39
MAOA P21397 2/20 0.39
AOC3 Q16853 2/20 0.39
DAO P14920 1/20 0.39
PKM P14618 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25259 0.86
Anisole SCHEMBL28064391 0.76 CA4 (0.64) ALDH1A1RECQLKCNA3ALOX15LMNA
SCHEMBL13928658 0.73 ALDH1A1 (0.54) ALDH1A1RECQLHDAC1HDAC2LMNA
SCHEMBL717121 0.72 NQO1 (0.47) ALDH1A1RECQLKCNA3ALOX15LMNA
SCHEMBL23824908 0.71 ALDH1A1 (0.46) ALDH1A1RECQLKCNA3ALOX15HDAC1
SCHEMBL2099230 0.71 ALDH1A1 (0.53) ALDH1A1MAOBAOC3
SCHEMBL19337469 0.71 KCNA3 (0.46) ALDH1A1RECQLKCNA3ALOX15HDAC1
SCHEMBL2095932 0.71 MAOB (0.51) ALDH1A1LMNACYP2C19MEN1KMT2A
Butyl Alcohol SCHEMBL165960 0.71 LTA4H (0.55) ALDH1A1RECQLKCNA3LMNAMAOA
Benzaldehyde SCHEMBL27184249 0.71 ALDH1A1 (0.56) ALDH1A1RECQLKCNA3ALOX15CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6110501-A A TABLET THAT UTILIZES MICROCAPSULES WHEREIN AN ACTIVE SUBSTANCE FORMS THE CORE OF THE MICROCAPSULE AND OTHER CHEMICAL AGENTS(SEEDS) ARE DISPERSED THROUGHOUT THE MICROCAPSULE SHELL TO STRENGTHEN THE SHELL VERION INC. (US) 2000-08-29 US claimed